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A transcriptional evaluation of the melanoma and squamous cell carcinoma TIL compartment reveals an unexpected spectrum of exhausted and functional T cells.
Cameron CM, Richardson B, Golden JB, Phoon YP, Tamilselvan B, Pfannenstiel L, Thapaliya S, Roversi G, Gao XH, Zagore LL, Cameron MJ, Gastman BR. Cameron CM, et al. Among authors: thapaliya s. Front Oncol. 2023 Oct 30;13:1200387. doi: 10.3389/fonc.2023.1200387. eCollection 2023. Front Oncol. 2023. PMID: 38023136 Free PMC article.
A high OXPHOS CD8 T cell subset is predictive of immunotherapy resistance in melanoma patients.
Li C, Phoon YP, Karlinsey K, Tian YF, Thapaliya S, Thongkum A, Qu L, Matz AJ, Cameron M, Cameron C, Menoret A, Funchain P, Song JM, Diaz-Montero CM, Tamilselvan B, Golden JB, Cartwright M, Rodriguez A, Bonin C, Vella A, Zhou B, Gastman BR. Li C, et al. Among authors: thapaliya s. J Exp Med. 2022 Jan 3;219(1):e20202084. doi: 10.1084/jem.20202084. Epub 2021 Nov 22. J Exp Med. 2022. PMID: 34807232 Free PMC article.
Activated Protein Phosphatase 2A Disrupts Nutrient Sensing Balance Between Mechanistic Target of Rapamycin Complex 1 and Adenosine Monophosphate-Activated Protein Kinase, Causing Sarcopenia in Alcohol-Associated Liver Disease.
Davuluri G, Welch N, Sekar J, Gangadhariah M, Alsabbagh Alchirazi K, Mohan ML, Kumar A, Kant S, Thapaliya S, Stine M, McMullen MR, McCullough RL, Stark GR, Nagy LE, Naga Prasad SV, Dasarathy S. Davuluri G, et al. Among authors: thapaliya s. Hepatology. 2021 May;73(5):1892-1908. doi: 10.1002/hep.31524. Epub 2021 Apr 20. Hepatology. 2021. PMID: 32799332 Free PMC article.
Hyperammonemia in cirrhosis induces transcriptional regulation of myostatin by an NF-κB-mediated mechanism.
Qiu J, Thapaliya S, Runkana A, Yang Y, Tsien C, Mohan ML, Narayanan A, Eghtesad B, Mozdziak PE, McDonald C, Stark GR, Welle S, Naga Prasad SV, Dasarathy S. Qiu J, et al. Among authors: thapaliya s. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18162-7. doi: 10.1073/pnas.1317049110. Epub 2013 Oct 21. Proc Natl Acad Sci U S A. 2013. PMID: 24145431 Free PMC article.
57 results