Chen Y - Search Results

1

Three doses of COVID-19 mRNA vaccine induce class-switched antibody responses in inflammatory arthritis patients on immunomodulatory therapies.

Lee JM, Figueroa A, Sachithanandham J, Li M, Connolly CM, Shapiro JR, Chen Y, Jones M, Dhara VG, Towns M, Lee JS, Peralta SR, Milstone AM, Betenbaugh M, Debes AK, Blankson J, Sitaras I, Yoon S, Thompson EA, Bingham CO 3rd, Klein SL, Pekosz A, Bailey JR. Lee JM, et al. Among authors: chen y. Front Immunol. 2023 Oct 24;14:1266370. doi: 10.3389/fimmu.2023.1266370. eCollection 2023. Front Immunol. 2023. PMID: 38022602 Free PMC article.

2

A Linkage-specific Sialic Acid Labeling Strategy Reveals Different Site-specific Glycosylation Patterns in SARS-CoV-2 Spike Protein Produced in CHO and HEK Cell Substrates.

Wang Q, Wang Y, Yang S, Lin C, Aliyu L, Chen Y, Parsons L, Tian Y, Jia H, Pekosz A, Betenbaugh MJ, Cipollo JF. Wang Q, et al. Among authors: chen y. Front Chem. 2021 Sep 24;9:735558. doi: 10.3389/fchem.2021.735558. eCollection 2021. Front Chem. 2021. PMID: 34631661 Free PMC article.

3

Reconstruction of reverse transsulfuration pathway enables cysteine biosynthesis and enhances resilience to oxidative stress in Chinese Hamster Ovary cells.

Chen Y, Betenbaugh MJ. Chen Y, et al. Metab Eng. 2023 Mar;76:204-214. doi: 10.1016/j.ymben.2023.02.010. Epub 2023 Feb 21. Metab Eng. 2023. PMID: 36822463

4

A genome-scale nutrient minimization forecast algorithm for controlling essential amino acid levels in CHO cell cultures.

Chen Y, Liu X, Anderson JYL, Naik HM, Dhara VG, Chen X, Harris GA, Betenbaugh MJ. Chen Y, et al. Among authors: chen x. Biotechnol Bioeng. 2022 Feb;119(2):435-451. doi: 10.1002/bit.27994. Epub 2021 Dec 2. Biotechnol Bioeng. 2022. PMID: 34811743

5

Design and Production of Bispecific Antibodies.

Wang Q, Chen Y, Park J, Liu X, Hu Y, Wang T, McFarland K, Betenbaugh MJ. Wang Q, et al. Among authors: chen y. Antibodies (Basel). 2019 Aug 2;8(3):43. doi: 10.3390/antib8030043. Antibodies (Basel). 2019. PMID: 31544849 Free PMC article. Review.

6

Optimization of nutrient utilization efficiency and productivity for algal cultures under light and dark cycles using genome-scale model process control.

Li CT, Eng R, Zuniga C, Huang KW, Chen Y, Zengler K, Betenbaugh MJ. Li CT, et al. Among authors: chen y. NPJ Syst Biol Appl. 2023 Mar 15;9(1):7. doi: 10.1038/s41540-022-00260-7. NPJ Syst Biol Appl. 2023. PMID: 36922521 Free PMC article.

7

An unconventional uptake rate objective function approach enhances applicability of genome-scale models for mammalian cells.

Chen Y, McConnell BO, Gayatri Dhara V, Mukesh Naik H, Li CT, Antoniewicz MR, Betenbaugh MJ. Chen Y, et al. NPJ Syst Biol Appl. 2019 Jul 23;5:25. doi: 10.1038/s41540-019-0103-6. eCollection 2019. NPJ Syst Biol Appl. 2019. PMID: 31341637 Free PMC article.

8

Combining Butyrated ManNAc with Glycoengineered CHO Cells Improves EPO Glycan Quality and Production.

Wang Q, Chung CY, Yang W, Yang G, Chough S, Chen Y, Yin B, Bhattacharya R, Hu Y, Saeui CT, Yarema KJ, Betenbaugh MJ, Zhang H. Wang Q, et al. Among authors: chen y. Biotechnol J. 2019 Apr;14(4):e1800186. doi: 10.1002/biot.201800186. Epub 2018 Oct 8. Biotechnol J. 2019. PMID: 30221828

9

Metabolic engineering challenges of extending N-glycan pathways in Chinese hamster ovary cells.

Wang Q, Wang T, Yang S, Sha S, Wu WW, Chen Y, Paul JT, Shen RF, Cipollo JF, Betenbaugh MJ. Wang Q, et al. Among authors: chen y. Metab Eng. 2020 Sep;61:301-314. doi: 10.1016/j.ymben.2020.06.007. Epub 2020 Jul 12. Metab Eng. 2020. PMID: 32663509

10

Utilizing genome-scale models to optimize nutrient supply for sustained algal growth and lipid productivity.

Li CT, Yelsky J, Chen Y, Zuñiga C, Eng R, Jiang L, Shapiro A, Huang KW, Zengler K, Betenbaugh MJ. Li CT, et al. Among authors: chen y. NPJ Syst Biol Appl. 2019 Sep 24;5:33. doi: 10.1038/s41540-019-0110-7. eCollection 2019. NPJ Syst Biol Appl. 2019. PMID: 31583115 Free PMC article.

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