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SIRT2 transgenic over-expression does not impact lifespan in mice.
Wu LE, Fiveash CE, Bentley NL, Kang MJ, Govindaraju H, Barbour JA, Wilkins BP, Hancock SE, Madawala R, Das A, Massudi H, Li C, Kim LJ, Wong ASA, Marinova MB, Sultani G, Das A, Youngson NA, Le Couteur DG, Sinclair DA, Turner N. Wu LE, et al. Among authors: turner n. Aging Cell. 2023 Dec;22(12):e14027. doi: 10.1111/acel.14027. Epub 2023 Nov 27. Aging Cell. 2023. PMID: 38009412 Free PMC article.
IRS1-independent defects define major nodes of insulin resistance.
Hoehn KL, Hohnen-Behrens C, Cederberg A, Wu LE, Turner N, Yuasa T, Ebina Y, James DE. Hoehn KL, et al. Among authors: turner n. Cell Metab. 2008 May;7(5):421-33. doi: 10.1016/j.cmet.2008.04.005. Cell Metab. 2008. PMID: 18460333 Free PMC article.
The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice.
Solon-Biet SM, McMahon AC, Ballard JW, Ruohonen K, Wu LE, Cogger VC, Warren A, Huang X, Pichaud N, Melvin RG, Gokarn R, Khalil M, Turner N, Cooney GJ, Sinclair DA, Raubenheimer D, Le Couteur DG, Simpson SJ. Solon-Biet SM, et al. Among authors: turner n. Cell Metab. 2014 Mar 4;19(3):418-30. doi: 10.1016/j.cmet.2014.02.009. Cell Metab. 2014. PMID: 24606899 Free PMC article.
The Influence of Macronutrients on Splanchnic and Hepatic Lymphocytes in Aging Mice.
Le Couteur DG, Tay SS, Solon-Biet S, Bertolino P, McMahon AC, Cogger VC, Colakoglu F, Warren A, Holmes AJ, Pichaud N, Horan M, Correa C, Melvin RG, Turner N, Ballard JW, Ruohonen K, Raubenheimer D, Simpson SJ. Le Couteur DG, et al. Among authors: turner n. J Gerontol A Biol Sci Med Sci. 2015 Dec;70(12):1499-507. doi: 10.1093/gerona/glu196. Epub 2014 Oct 21. J Gerontol A Biol Sci Med Sci. 2015. PMID: 25335766
1,876 results