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Characterisation and prion transmission study in mice with genetic reduction of sporadic Creutzfeldt-Jakob disease risk gene Stx6.
Jones E, Hill E, Linehan J, Nazari T, Caulder A, Codner GF, Hutchison M, Mackenzie M, Farmer M, Coysh T, De Oliveira MW, Al-Doujaily H, Sandberg M, Viré E, Cunningham TJ, Asante EA, Brandner S, Collinge J, Mead S. Jones E, et al. Among authors: linehan j. Neurobiol Dis. 2024 Jan;190:106363. doi: 10.1016/j.nbd.2023.106363. Epub 2023 Nov 22. Neurobiol Dis. 2024. PMID: 37996040 Free PMC article.
Dissociation of pathological and molecular phenotype of variant Creutzfeldt-Jakob disease in transgenic human prion protein 129 heterozygous mice.
Asante EA, Linehan JM, Gowland I, Joiner S, Fox K, Cooper S, Osiguwa O, Gorry M, Welch J, Houghton R, Desbruslais M, Brandner S, Wadsworth JD, Collinge J. Asante EA, et al. Among authors: linehan jm. Proc Natl Acad Sci U S A. 2006 Jul 11;103(28):10759-64. doi: 10.1073/pnas.0604292103. Epub 2006 Jun 29. Proc Natl Acad Sci U S A. 2006. PMID: 16809423 Free PMC article.
Kuru prions and sporadic Creutzfeldt-Jakob disease prions have equivalent transmission properties in transgenic and wild-type mice.
Wadsworth JD, Joiner S, Linehan JM, Desbruslais M, Fox K, Cooper S, Cronier S, Asante EA, Mead S, Brandner S, Hill AF, Collinge J. Wadsworth JD, et al. Among authors: linehan jm. Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3885-90. doi: 10.1073/pnas.0800190105. Epub 2008 Mar 3. Proc Natl Acad Sci U S A. 2008. PMID: 18316717 Free PMC article.
Molecular diagnosis of human prion disease.
Wadsworth JD, Powell C, Beck JA, Joiner S, Linehan JM, Brandner S, Mead S, Collinge J. Wadsworth JD, et al. Among authors: linehan jm. Methods Mol Biol. 2008;459:197-227. doi: 10.1007/978-1-59745-234-2_14. Methods Mol Biol. 2008. PMID: 18576157
A naturally occurring variant of the human prion protein completely prevents prion disease.
Asante EA, Smidak M, Grimshaw A, Houghton R, Tomlinson A, Jeelani A, Jakubcova T, Hamdan S, Richard-Londt A, Linehan JM, Brandner S, Alpers M, Whitfield J, Mead S, Wadsworth JD, Collinge J. Asante EA, et al. Among authors: linehan jm. Nature. 2015 Jun 25;522(7557):478-81. doi: 10.1038/nature14510. Epub 2015 Jun 10. Nature. 2015. PMID: 26061765 Free PMC article.
322 results