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Evolution-inspired engineering of nonribosomal peptide synthetases.
Bozhüyük KAJ, Präve L, Kegler C, Schenk L, Kaiser S, Schelhas C, Shi YN, Kuttenlochner W, Schreiber M, Kandler J, Alanjary M, Mohiuddin TM, Groll M, Hochberg GKA, Bode HB. Bozhüyük KAJ, et al. Science. 2024 Mar 22;383(6689):eadg4320. doi: 10.1126/science.adg4320. Epub 2024 Mar 22. Science. 2024. PMID: 38513038
ABC-HuMi: the Atlas of Biosynthetic Gene Clusters in the Human Microbiome.
Hirsch P, Tagirdzhanov A, Kushnareva A, Olkhovskii I, Graf S, Schmartz GP, Hegemann JD, Bozhüyük KAJ, Müller R, Keller A, Gurevich A. Hirsch P, et al. Among authors: bozhuyuk kaj. Nucleic Acids Res. 2024 Jan 5;52(D1):D579-D585. doi: 10.1093/nar/gkad1086. Nucleic Acids Res. 2024. PMID: 37994699 Free PMC article.
Genome Mining Enabled by Biosynthetic Characterization Uncovers a Class of Benzoxazolinate-Containing Natural Products in Diverse Bacteria.
Shi YM, Crames JJ, Czech L, Bozhüyük KAJ, Shi YN, Hirschmann M, Lamberth S, Claus P, Paczia N, Rückert C, Kalinowski J, Bange G, Bode HB. Shi YM, et al. Among authors: bozhuyuk kaj. Angew Chem Int Ed Engl. 2022 Dec 19;61(51):e202206106. doi: 10.1002/anie.202206106. Epub 2022 Nov 17. Angew Chem Int Ed Engl. 2022. PMID: 36198080 Free PMC article.
Bifurcation drives the evolution of assembly-line biosynthesis.
Booth TJ, Bozhüyük KAJ, Liston JD, Batey SFD, Lacey E, Wilkinson B. Booth TJ, et al. Among authors: bozhuyuk kaj. Nat Commun. 2022 Jun 17;13(1):3498. doi: 10.1038/s41467-022-30950-z. Nat Commun. 2022. PMID: 35715397 Free PMC article.
A Photorhabdus natural product inhibits insect juvenile hormone epoxide hydrolase.
Nollmann FI, Heinrich AK, Brachmann AO, Morisseau C, Mukherjee K, Casanova-Torres ÁM, Strobl F, Kleinhans D, Kinski S, Schultz K, Beeton ML, Kaiser M, Chu YY, Phan Ke L, Thanwisai A, Bozhüyük KA, Chantratita N, Götz F, Waterfield NR, Vilcinskas A, Stelzer EH, Goodrich-Blair H, Hammock BD, Bode HB. Nollmann FI, et al. Chembiochem. 2015 Mar 23;16(5):766-71. doi: 10.1002/cbic.201402650. Epub 2015 Feb 25. Chembiochem. 2015. PMID: 25711603 Free PMC article.
14 results