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Preclinical, randomized phase 1, and compassionate use evaluation of REGN4461, a leptin receptor agonist antibody for leptin deficiency.
Altarejos JY, Pangilinan J, Podgrabinska S, Akinci B, Foss-Freitas M, Neidert AH, Ray Y, Zheng W, Kim S, Kamat V, Huang M, Min S, Mastaitis J, Dominguez-Gutierrez G, Kim JH, Stevis P, Huang T, Zambrowicz B, Olson WC, Godin S, Bradley E, Gewitz AD, Baker M, Hench R, Davenport MS, Chenevert TL, DiPaola F, Yancopoulos GD, Murphy AJ, Herman GA, Musser BJ, Dansky H, Harp J, Gromada J, Sleeman MW, Oral EA, Olenchock BA. Altarejos JY, et al. Among authors: min s. Sci Transl Med. 2023 Nov 22;15(723):eadd4897. doi: 10.1126/scitranslmed.add4897. Epub 2023 Nov 22. Sci Transl Med. 2023. PMID: 37992152 Clinical Trial.
Activin E-ACVR1C cross talk controls energy storage via suppression of adipose lipolysis in mice.
Adam RC, Pryce DS, Lee JS, Zhao Y, Mintah IJ, Min S, Halasz G, Mastaitis J, Atwal GS, Aykul S, Idone V, Economides AN, Lotta LA, Murphy AJ, Yancopoulos GD, Sleeman MW, Gusarova V. Adam RC, et al. Among authors: min s. Proc Natl Acad Sci U S A. 2023 Aug 8;120(32):e2309967120. doi: 10.1073/pnas.2309967120. Epub 2023 Jul 31. Proc Natl Acad Sci U S A. 2023. PMID: 37523551 Free PMC article.
GPR17 gene disruption does not alter food intake or glucose homeostasis in mice.
Mastaitis J, Min S, Elvert R, Kannt A, Xin Y, Ochoa F, Gale NW, Valenzuela DM, Murphy AJ, Yancopoulos GD, Gromada J. Mastaitis J, et al. Among authors: min s. Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):1845-9. doi: 10.1073/pnas.1424968112. Epub 2015 Jan 26. Proc Natl Acad Sci U S A. 2015. PMID: 25624481 Free PMC article.
Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2.
Bashore FM, Min SM, Chen X, Howell S, Rinderle CH, Morel G, Silvaroli JA, Wells CI, Bunnell BA, Drewry DH, Pabla NS, Ultanir SK, Bullock AN, Axtman AD. Bashore FM, et al. Among authors: min sm. bioRxiv [Preprint]. 2024 May 14:2024.05.12.593776. doi: 10.1101/2024.05.12.593776. bioRxiv. 2024. PMID: 38798634 Free PMC article. Preprint.
3,035 results