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Preclinical, randomized phase 1, and compassionate use evaluation of REGN4461, a leptin receptor agonist antibody for leptin deficiency.
Altarejos JY, Pangilinan J, Podgrabinska S, Akinci B, Foss-Freitas M, Neidert AH, Ray Y, Zheng W, Kim S, Kamat V, Huang M, Min S, Mastaitis J, Dominguez-Gutierrez G, Kim JH, Stevis P, Huang T, Zambrowicz B, Olson WC, Godin S, Bradley E, Gewitz AD, Baker M, Hench R, Davenport MS, Chenevert TL, DiPaola F, Yancopoulos GD, Murphy AJ, Herman GA, Musser BJ, Dansky H, Harp J, Gromada J, Sleeman MW, Oral EA, Olenchock BA. Altarejos JY, et al. Among authors: akinci b. Sci Transl Med. 2023 Nov 22;15(723):eadd4897. doi: 10.1126/scitranslmed.add4897. Epub 2023 Nov 22. Sci Transl Med. 2023. PMID: 37992152 Clinical Trial.
Clinical presentations, metabolic abnormalities and end-organ complications in patients with familial partial lipodystrophy.
Akinci B, Onay H, Demir T, Savas-Erdeve Ş, Gen R, Simsir IY, Keskin FE, Erturk MS, Uzum AK, Yaylali GF, Ozdemir NK, Atik T, Ozen S, Yurekli BS, Apaydin T, Altay C, Akinci G, Demir L, Comlekci A, Secil M, Oral EA. Akinci B, et al. Among authors: akinci g. Metabolism. 2017 Jul;72:109-119. doi: 10.1016/j.metabol.2017.04.010. Epub 2017 Apr 27. Metabolism. 2017. PMID: 28641778
Renal complications of lipodystrophy: A closer look at the natural history of kidney disease.
Akinci B, Unlu SM, Celik A, Simsir IY, Sen S, Nur B, Keskin FE, Ozgen Saydam B, Kutbay Ozdemir N, Sarer Yurekli B, Ergur BU, Sonmez M, Atik T, Arslan A, Demir T, Altay C, Tunc UA, Arkan T, Gen R, Eren E, Akinci G, Yilmaz AA, Bilen H, Ozen S, Celtik A, Savas Erdeve S, Cetinkaya S, Onay H, Sarioglu S, Oral EA. Akinci B, et al. Among authors: akinci g. Clin Endocrinol (Oxf). 2018 Jul;89(1):65-75. doi: 10.1111/cen.13732. Epub 2018 May 17. Clin Endocrinol (Oxf). 2018. PMID: 29722904 Free PMC article.
Update on Therapeutic Options in Lipodystrophy.
Akinci B, Meral R, Oral EA. Akinci B, et al. Curr Diab Rep. 2018 Oct 29;18(12):139. doi: 10.1007/s11892-018-1100-7. Curr Diab Rep. 2018. PMID: 30370487 Review.
Diagnostic strategies and clinical management of lipodystrophy.
Foss-Freitas MC, Akinci B, Luo Y, Stratton A, Oral EA. Foss-Freitas MC, et al. Among authors: akinci b. Expert Rev Endocrinol Metab. 2020 Mar;15(2):95-114. doi: 10.1080/17446651.2020.1735360. Expert Rev Endocrinol Metab. 2020. PMID: 32368944 Review.
168 results