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Summary of Research: An Anti-OX40 Antibody to Treat Moderate-to-Severe Atopic Dermatitis: A Multicentre, Double-Blind, Placebo-Controlled Phase 2b Study.
Guttman-Yassky E, Simpson EL, Reich K, Kabashima K, Igawa K, Suzuki T, Mano H, Matsui T, Esfandiari E, Furue M. Guttman-Yassky E, et al. Among authors: mano h. Adv Ther. 2024 Mar;41(3):928-931. doi: 10.1007/s12325-023-02755-z. Epub 2024 Jan 8. Adv Ther. 2024. PMID: 38185777 Free PMC article. Clinical Trial.
Collagen-derived dipeptide prolyl-hydroxyproline cooperates with Foxg1 to activate the PGC-1α promoter and induce brown adipocyte-like phenotype in rosiglitazone-treated C3H10T1/2 cells.
Nomura K, Kimira Y, Kobayashi R, Shiobara Y, Osawa Y, Kataoka-Matsushita A, Shimizu J, Wada M, Mano H. Nomura K, et al. Among authors: mano h. Front Nutr. 2024 May 15;11:1375532. doi: 10.3389/fnut.2024.1375532. eCollection 2024. Front Nutr. 2024. PMID: 38812940 Free PMC article.
Maintenance of R-loop structures by phosphorylated hTERT preserves genome integrity.
Machitani M, Nomura A, Yamashita T, Yasukawa M, Ueki S, Fujita KI, Ueno T, Yamashita A, Tanzawa Y, Watanabe M, Taniguchi T, Saitoh N, Kaneko S, Kato Y, Mano H, Masutomi K. Machitani M, et al. Among authors: mano h. Nat Cell Biol. 2024 May 28. doi: 10.1038/s41556-024-01427-6. Online ahead of print. Nat Cell Biol. 2024. PMID: 38806647
A molecular glue RBM39-degrader induces synthetic lethality in cancer cells with homologous recombination repair deficiency.
Kohsaka S, Yagishita S, Shirai Y, Matsuno Y, Ueno T, Kojima S, Ikeuchi H, Ikegami M, Kitada R, Yoshioka KI, Toshimitsu K, Tabata K, Yokoi A, Doi T, Yamamoto N, Owa T, Hamada A, Mano H. Kohsaka S, et al. Among authors: mano h. NPJ Precis Oncol. 2024 May 24;8(1):117. doi: 10.1038/s41698-024-00610-0. NPJ Precis Oncol. 2024. PMID: 38789724 Free PMC article.
Rapid Response to Lenvatinib and Disease Flare After Discontinuation in a Patient With Thymic Carcinoma Harboring KIT Exon 11 Mutation: A Case Report.
Torasawa M, Yoshida T, Shiraishi K, Goto N, Ueno T, Ichikawa H, Yagishita S, Kohsaka S, Goto Y, Yatabe Y, Hamada A, Mano H, Ohe Y. Torasawa M, et al. Among authors: mano h. JTO Clin Res Rep. 2024 Feb 28;5(4):100657. doi: 10.1016/j.jtocrr.2024.100657. eCollection 2024 Apr. JTO Clin Res Rep. 2024. PMID: 38706977 Free PMC article.
574 results