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The multi-factorial nature of clinical multidrug resistance in cancer.
Assaraf YG, Brozovic A, Gonçalves AC, Jurkovicova D, Linē A, Machuqueiro M, Saponara S, Sarmento-Ribeiro AB, Xavier CPR, Vasconcelos MH. Assaraf YG, et al. Among authors: saponara s. Drug Resist Updat. 2019 Sep;46:100645. doi: 10.1016/j.drup.2019.100645. Epub 2019 Sep 17. Drug Resist Updat. 2019. PMID: 31585396 Review.
Repurposing old drugs to fight multidrug resistant cancers.
Dinić J, Efferth T, García-Sosa AT, Grahovac J, Padrón JM, Pajeva I, Rizzolio F, Saponara S, Spengler G, Tsakovska I. Dinić J, et al. Among authors: saponara s. Drug Resist Updat. 2020 Sep;52:100713. doi: 10.1016/j.drup.2020.100713. Epub 2020 Jun 25. Drug Resist Updat. 2020. PMID: 32615525 Review.
Negative chronotropism, positive inotropism and lusitropism of 3,5-di-t-butyl-4-hydroxyanisole (DTBHA) on rat heart preparations occur through reduction of RyR2 Ca2+ leak.
Pessina F, Gamberucci A, Chen J, Liu B, Vangheluwe P, Gorelli B, Lorenzini S, Spiga O, Trezza A, Sgaragli G, Saponara S. Pessina F, et al. Among authors: saponara s. Biochem Pharmacol. 2018 Sep;155:434-443. doi: 10.1016/j.bcp.2018.07.026. Epub 2018 Jul 21. Biochem Pharmacol. 2018. PMID: 30036502
101 results