Arnsten A - Search Results

1

The regional pattern of age-related synaptic loss in the human brain differs from gray matter volume loss: in vivo PET measurement with [¹¹C]UCB-J.

Toyonaga T, Khattar N, Wu Y, Lu Y, Naganawa M, Gallezot JD, Matuskey D, Mecca AP, Pittman B, Dias M, Nabulsi NB, Finnema SJ, Chen MK, Arnsten A, Radhakrishnan R, Skosnik PD, D'Souza DC, Esterlis I, Huang Y, van Dyck CH, Carson RE. Toyonaga T, et al. Among authors: arnsten a. Eur J Nucl Med Mol Imaging. 2024 Mar;51(4):1012-1022. doi: 10.1007/s00259-023-06487-8. Epub 2023 Nov 13. Eur J Nucl Med Mol Imaging. 2024. PMID: 37955791

2

The effects of 5-HT3 receptor antagonists on cognitive performance in aged monkeys.

Arnsten AF, Lin CH, Van Dyck CH, Stanhope KJ. Arnsten AF, et al. Neurobiol Aging. 1997 Jan-Feb;18(1):21-8. doi: 10.1016/s0197-4580(96)00162-5. Neurobiol Aging. 1997. PMID: 8983029 Free article.

3

The acetylcholine releaser linopirdine increases parietal regional cerebral blood flow in Alzheimer's disease.

van Dyck CH, Lin CH, Robinson R, Cellar J, Smith EO, Nelson JC, Arnsten AF, Hoffer PB. van Dyck CH, et al. Among authors: arnsten af. Psychopharmacology (Berl). 1997 Aug;132(3):217-26. doi: 10.1007/s002130050339. Psychopharmacology (Berl). 1997. PMID: 9292621 Clinical Trial.

4

The alpha-2A-adrenoceptor agonist, guanfacine, increases regional cerebral blood flow in dorsolateral prefrontal cortex of monkeys performing a spatial working memory task.

Avery RA, Franowicz JS, Studholme C, van Dyck CH, Arnsten AF. Avery RA, et al. Among authors: arnsten af. Neuropsychopharmacology. 2000 Sep;23(3):240-9. doi: 10.1016/S0893-133X(00)00111-1. Neuropsychopharmacology. 2000. PMID: 10942848

5

Alpha2A-adrenoceptor stimulation improves prefrontal cortical regulation of behavior through inhibition of cAMP signaling in aging animals.

Ramos BP, Stark D, Verduzco L, van Dyck CH, Arnsten AF. Ramos BP, et al. Learn Mem. 2006 Nov-Dec;13(6):770-6. doi: 10.1101/lm.298006. Epub 2006 Nov 13. Learn Mem. 2006. PMID: 17101879 Free PMC article.

6

Striatal dopamine transporters correlate with simple reaction time in elderly subjects.

van Dyck CH, Avery RA, MacAvoy MG, Marek KL, Quinlan DM, Baldwin RM, Seibyl JP, Innis RB, Arnsten AF. van Dyck CH, et al. Among authors: arnsten af. Neurobiol Aging. 2008 Aug;29(8):1237-46. doi: 10.1016/j.neurobiolaging.2007.02.012. Epub 2007 Mar 23. Neurobiol Aging. 2008. PMID: 17363113 Free PMC article.

7

Inhibition of protein kinase C signaling protects prefrontal cortex dendritic spines and cognition from the effects of chronic stress.

Hains AB, Vu MA, Maciejewski PK, van Dyck CH, Gottron M, Arnsten AF. Hains AB, et al. Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17957-62. doi: 10.1073/pnas.0908563106. Epub 2009 Sep 11. Proc Natl Acad Sci U S A. 2009. PMID: 19805148 Free PMC article.

8

The aged rhesus macaque manifests Braak stage III/IV Alzheimer's-like pathology.

Paspalas CD, Carlyle BC, Leslie S, Preuss TM, Crimins JL, Huttner AJ, van Dyck CH, Rosene DL, Nairn AC, Arnsten AFT. Paspalas CD, et al. Alzheimers Dement. 2018 May;14(5):680-691. doi: 10.1016/j.jalz.2017.11.005. Epub 2017 Dec 11. Alzheimers Dement. 2018. PMID: 29241829 Free PMC article.

9

Guanfacine treatment for prefrontal cognitive dysfunction in older participants: a randomized clinical trial.

Barcelos NM, Van Ness PH, Wagner AF, MacAvoy MG, Mecca AP, Anderson GM, Trentalange M, Hawkins KA, Sano M, Arnsten AFT, van Dyck CH. Barcelos NM, et al. Among authors: arnsten aft. Neurobiol Aging. 2018 Oct;70:117-124. doi: 10.1016/j.neurobiolaging.2018.05.033. Epub 2018 May 31. Neurobiol Aging. 2018. PMID: 30007160 Free PMC article. Clinical Trial.

10

Assessing Synaptic Density in Alzheimer Disease With Synaptic Vesicle Glycoprotein 2A Positron Emission Tomographic Imaging.

Chen MK, Mecca AP, Naganawa M, Finnema SJ, Toyonaga T, Lin SF, Najafzadeh S, Ropchan J, Lu Y, McDonald JW, Michalak HR, Nabulsi NB, Arnsten AFT, Huang Y, Carson RE, van Dyck CH. Chen MK, et al. JAMA Neurol. 2018 Oct 1;75(10):1215-1224. doi: 10.1001/jamaneurol.2018.1836. JAMA Neurol. 2018. PMID: 30014145 Free PMC article.

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