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Topical delivery of seriniquinone for treatment of skin cancer and fungal infections is enabled by a liquid crystalline lamellar phase.
Miguel RDA, Hirata AS, Salata GC, Apolinário AC, Barroso VM, Ishida K, La Clair JJ, Fenical W, Martins TS, Costa-Lotufo LV, Lopes LB. Miguel RDA, et al. Among authors: la clair jj. Eur J Pharm Sci. 2024 Jan 1;192:106635. doi: 10.1016/j.ejps.2023.106635. Epub 2023 Nov 11. Eur J Pharm Sci. 2024. PMID: 37952683 Free article.
Visualizing the Interface of Biotin and Fatty Acid Biosynthesis through SuFEx Probes.
Chen A, Re RN, Davis TD, Tran K, Moriuchi YW, Wu S, La Clair JJ, Louie GV, Bowman ME, Clarke DJ, Mackay CL, Campopiano DJ, Noel JP, Burkart MD. Chen A, et al. Among authors: la clair jj. J Am Chem Soc. 2024 Jan 17;146(2):1388-1395. doi: 10.1021/jacs.3c10181. Epub 2024 Jan 4. J Am Chem Soc. 2024. PMID: 38176024
Masked cerulenin enables a dual-site selective protein crosslink.
Jiang Z, Chen A, Chen J, Sekhon A, Louie GV, Noel JP, La Clair JJ, Burkart MD. Jiang Z, et al. Among authors: la clair jj. Chem Sci. 2023 Sep 8;14(39):10925-10933. doi: 10.1039/d3sc02864j. eCollection 2023 Oct 11. Chem Sci. 2023. PMID: 37829009 Free PMC article.
Interface Engineering of Carrier-Protein-Dependent Metabolic Pathways.
Sztain T, Corpuz JC, Bartholow TG, Sanlley Hernandez JO, Jiang Z, Mellor DA, Heberlig GW, La Clair JJ, McCammon JA, Burkart MD. Sztain T, et al. Among authors: la clair jj. ACS Chem Biol. 2023 Sep 15;18(9):2014-2022. doi: 10.1021/acschembio.3c00238. Epub 2023 Sep 6. ACS Chem Biol. 2023. PMID: 37671411
Nanoscaled Discovery of a Shunt Rifamycin from Salinispora arenicola Using a Three-Color GFP-Tagged Staphylococcus aureus Macrophage Infection Assay.
Pham NT, Alves J, Sargison FA, Cullum R, Wildenhain J, Fenical W, Butler MS, Mead DA, Duggan BM, Fitzgerald JR, La Clair JJ, Auer M. Pham NT, et al. Among authors: la clair jj. ACS Infect Dis. 2023 Aug 11;9(8):1499-1507. doi: 10.1021/acsinfecdis.3c00049. Epub 2023 Jul 11. ACS Infect Dis. 2023. PMID: 37433130 Free PMC article.
Synthase-selected sorting approach identifies a beta-lactone synthase in a nudibranch symbiotic bacterium.
Džunková M, La Clair JJ, Tyml T, Doud D, Schulz F, Piquer-Esteban S, Porcel Sanchis D, Osborn A, Robinson D, Louie KB, Bowen BP, Bowers RM, Lee J, Arnau V, Díaz-Villanueva W, Stepanauskas R, Gosliner T, Date SV, Northen TR, Cheng JF, Burkart MD, Woyke T. Džunková M, et al. Among authors: la clair jj. Microbiome. 2023 Jun 13;11(1):130. doi: 10.1186/s40168-023-01560-8. Microbiome. 2023. PMID: 37312139 Free PMC article.
Stereochemical Control of Splice Modulation in FD-895 Analogues.
Chan WC, Trieger KA, La Clair JJ, Jamieson CHM, Burkart MD. Chan WC, et al. Among authors: la clair jj. J Med Chem. 2023 May 25;66(10):6577-6590. doi: 10.1021/acs.jmedchem.2c01893. Epub 2023 May 8. J Med Chem. 2023. PMID: 37155693 Free PMC article.
Detection and targeting of splicing deregulation in pediatric acute myeloid leukemia stem cells.
van der Werf I, Mondala PK, Steel SK, Balaian L, Ladel L, Mason CN, Diep RH, Pham J, Cloos J, Kaspers GJL, Chan WC, Mark A, La Clair JJ, Wentworth P, Fisch KM, Crews LA, Whisenant TC, Burkart MD, Donohoe ME, Jamieson CHM. van der Werf I, et al. Among authors: la clair jj. Cell Rep Med. 2023 Mar 21;4(3):100962. doi: 10.1016/j.xcrm.2023.100962. Epub 2023 Mar 7. Cell Rep Med. 2023. PMID: 36889320 Free PMC article.
126 results