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Randomised clinical trial: Design of the SYNERGY-NASH phase 2b trial to evaluate tirzepatide as a treatment for metabolic dysfunction-associated steatohepatitis and modification of screening strategy to reduce screen failures.
Vuppalanchi R, Loomba R, Sanyal AJ, Nikooie A, Tang Y, Robins DA, Brouwers B, Hartman ML. Vuppalanchi R, et al. Among authors: brouwers b. Aliment Pharmacol Ther. 2024 May 20. doi: 10.1111/apt.18042. Online ahead of print. Aliment Pharmacol Ther. 2024. PMID: 38768298
Human loss-of-function variants in the serotonin 2C receptor associated with obesity and maladaptive behavior.
He Y, Brouwers B, Liu H, Liu H, Lawler K, Mendes de Oliveira E, Lee DK, Yang Y, Cox AR, Keogh JM, Henning E, Bounds R, Perdikari A, Ayinampudi V, Wang C, Yu M, Tu L, Zhang N, Yin N, Han J, Scarcelli NA, Yan Z, Conde KM, Potts C, Bean JC, Wang M, Hartig SM, Liao L, Xu J, Barroso I, Mokrosinski J, Xu Y, Sadaf Farooqi I. He Y, et al. Among authors: brouwers b. Nat Med. 2022 Dec;28(12):2537-2546. doi: 10.1038/s41591-022-02106-5. Epub 2022 Dec 19. Nat Med. 2022. PMID: 36536256 Free PMC article.
Evaluate the safety and efficacy of dura sealant patch in reducing cerebrospinal fluid leakage following elective cranial surgery (ENCASE II): study protocol for a randomized, two-arm, multicenter trial.
Carlson AP, Slot EMH, van Doormaal TPC; ENCASE II study group; Voormolen EHJ, Dankbaar JW, Depauw P, Brouwers B, Germans MR, Baert E, Vandersteene J, Freyschlag CF, Freyschlag J, Thomé C, Zenga F, Penner F, Abdulazim A, Sabel M, Rapp M, Beez T, Zuccarello M, Sauvageau E, Abdullah K, Welch B, Langer D, Ellis J, Dehdashti A, VanGompel J, Bendok B, Chaichana K, Liu J, Dogan A, Lim MK, Hayden MG. Carlson AP, et al. Among authors: brouwers b. Trials. 2022 Jul 20;23(1):581. doi: 10.1186/s13063-022-06490-8. Trials. 2022. PMID: 35858894 Free PMC article.
Nanobody-based retargeting of an oncolytic herpesvirus for eliminating CXCR4+ GBM cells: A proof of principle.
Sanchez Gil J, Dubois M, Neirinckx V, Lombard A, Coppieters N, D'Arrigo P, Isci D, Aldenhoff T, Brouwers B, Lassence C, Rogister B, Lebrun M, Sadzot-Delvaux C. Sanchez Gil J, et al. Among authors: brouwers b. Mol Ther Oncolytics. 2022 Jun 6;26:35-48. doi: 10.1016/j.omto.2022.06.002. eCollection 2022 Sep 15. Mol Ther Oncolytics. 2022. PMID: 35784400 Free PMC article.
Long term outcome data from the EORTC 75111-10114 ETF/BCG randomized phase II study: Pertuzumab and trastuzumab with or without metronomic chemotherapy for older patients with HER2-positive metastatic breast cancer, followed by T-DM1 after progression.
Wildiers H, Meyskens T, Marréaud S, Lago LD, Vuylsteke P, Curigliano G, Waters S, Brouwers B, Meulemans B, Sousa B, Poncet C, Brain E. Wildiers H, et al. Among authors: brouwers b. Breast. 2022 Aug;64:100-111. doi: 10.1016/j.breast.2022.05.004. Epub 2022 May 20. Breast. 2022. PMID: 35636341 Free PMC article. Clinical Trial.
Effect of tirzepatide versus insulin degludec on liver fat content and abdominal adipose tissue in people with type 2 diabetes (SURPASS-3 MRI): a substudy of the randomised, open-label, parallel-group, phase 3 SURPASS-3 trial.
Gastaldelli A, Cusi K, Fernández Landó L, Bray R, Brouwers B, Rodríguez Á. Gastaldelli A, et al. Among authors: brouwers b. Lancet Diabetes Endocrinol. 2022 Jun;10(6):393-406. doi: 10.1016/S2213-8587(22)00070-5. Epub 2022 Apr 22. Lancet Diabetes Endocrinol. 2022. PMID: 35468325 Clinical Trial.
76 results