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Stem cell-like reprogramming is required for leukemia-initiating activity in B-ALL.
Fregona V, Bayet M, Bouttier M, Largeaud L, Hamelle C, Jamrog LA, Prade N, Lagarde S, Hebrard S, Luquet I, Mansat-De Mas V, Nolla M, Pasquet M, Didier C, Khamlichi AA, Broccardo C, Delabesse É, Mancini SJC, Gerby B. Fregona V, et al. Among authors: bouttier m. J Exp Med. 2024 Jan 1;221(1):e20230279. doi: 10.1084/jem.20230279. Epub 2023 Nov 6. J Exp Med. 2024. PMID: 37930337 Free PMC article.
CDK12 is hyperactivated and a synthetic-lethal target in BRAF-mutated melanoma.
Houles T, Lavoie G, Nourreddine S, Cheung W, Vaillancourt-Jean É, Guérin CM, Bouttier M, Grondin B, Lin S, Saba-El-Leil MK, Angers S, Meloche S, Roux PP. Houles T, et al. Among authors: bouttier m. Nat Commun. 2022 Oct 29;13(1):6457. doi: 10.1038/s41467-022-34179-8. Nat Commun. 2022. PMID: 36309522 Free PMC article.
Dissecting the molecular mechanisms that impair stress granule formation in aging cells.
Moujaber O, Mahboubi H, Kodiha M, Bouttier M, Bednarz K, Bakshi R, White J, Larose L, Colmegna I, Stochaj U. Moujaber O, et al. Among authors: bouttier m. Biochim Biophys Acta Mol Cell Res. 2017 Mar;1864(3):475-486. doi: 10.1016/j.bbamcr.2016.12.008. Epub 2016 Dec 10. Biochim Biophys Acta Mol Cell Res. 2017. PMID: 27965113 Free article.
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