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Galectin-3 deficiency ameliorates fibrosis and remodeling in dilated cardiomyopathy mice with enhanced Mst1 signaling.
Nguyen MN, Ziemann M, Kiriazis H, Su Y, Thomas Z, Lu Q, Donner DG, Zhao WB, Rafehi H, Sadoshima J, McMullen JR, El-Osta A, Du XJ. Nguyen MN, et al. Among authors: mcmullen jr. Am J Physiol Heart Circ Physiol. 2019 Jan 1;316(1):H45-H60. doi: 10.1152/ajpheart.00609.2018. Epub 2018 Nov 2. Am J Physiol Heart Circ Physiol. 2019. PMID: 30387702 Free article.
Gene therapy targeting cardiac phosphoinositide 3-kinase (p110α) attenuates cardiac remodeling in type 2 diabetes.
Prakoso D, De Blasio MJ, Tate M, Kiriazis H, Donner DG, Qian H, Nash D, Deo M, Weeks KL, Parry LJ, Gregorevic P, McMullen JR, Ritchie RH. Prakoso D, et al. Among authors: mcmullen jr. Am J Physiol Heart Circ Physiol. 2020 Apr 1;318(4):H840-H852. doi: 10.1152/ajpheart.00632.2019. Epub 2020 Mar 6. Am J Physiol Heart Circ Physiol. 2020. PMID: 32142359 Free article.
FoxO1 is required for physiological cardiac hypertrophy induced by exercise but not by constitutively active PI3K.
Weeks KL, Tham YK, Yildiz SG, Alexander Y, Donner DG, Kiriazis H, Harmawan CA, Hsu A, Bernardo BC, Matsumoto A, DePinho RA, Abel ED, Woodcock EA, McMullen JR. Weeks KL, et al. Among authors: mcmullen jr. Am J Physiol Heart Circ Physiol. 2021 Apr 1;320(4):H1470-H1485. doi: 10.1152/ajpheart.00838.2020. Epub 2021 Feb 12. Am J Physiol Heart Circ Physiol. 2021. PMID: 33577435 Free article.
163 results