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Loss of PRDM11 promotes MYC-driven lymphomagenesis.
Fog CK, Asmar F, Côme C, Jensen KT, Johansen JV, Kheir TB, Jacobsen L, Friis C, Louw A, Rosgaard L, Øbro NF, Marquart HV, Anthonsen K, Braat AK, van Lohuizen M, Ralfkiaer E, Grønbæk K, Lund AH. Fog CK, et al. Among authors: gronbaek k. Blood. 2015 Feb 19;125(8):1272-81. doi: 10.1182/blood-2014-03-560805. Epub 2014 Dec 12. Blood. 2015. PMID: 25499759 Free article.
TP53 mutations identify younger mantle cell lymphoma patients who do not benefit from intensive chemoimmunotherapy.
Eskelund CW, Dahl C, Hansen JW, Westman M, Kolstad A, Pedersen LB, Montano-Almendras CP, Husby S, Freiburghaus C, Ek S, Pedersen A, Niemann C, Räty R, Brown P, Geisler CH, Andersen MK, Guldberg P, Jerkeman M, Grønbæk K. Eskelund CW, et al. Among authors: gronbaek k. Blood. 2017 Oct 26;130(17):1903-1910. doi: 10.1182/blood-2017-04-779736. Epub 2017 Aug 17. Blood. 2017. PMID: 28819011 Free article.
Vitamin C - A new player in regulation of the cancer epigenome.
Gillberg L, Ørskov AD, Liu M, Harsløf LBS, Jones PA, Grønbæk K. Gillberg L, et al. Among authors: gronbaek k. Semin Cancer Biol. 2018 Aug;51:59-67. doi: 10.1016/j.semcancer.2017.11.001. Epub 2017 Nov 2. Semin Cancer Biol. 2018. PMID: 29102482 Review.
Specific Lipid and Metabolic Profiles of R-CHOP-Resistant Diffuse Large B-Cell Lymphoma Elucidated by Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging and in Vivo Imaging.
Barré FPY, Claes BSR, Dewez F, Peutz-Kootstra C, Munch-Petersen HF, Grønbæk K, Lund AH, Heeren RMA, Côme C, Cillero-Pastor B. Barré FPY, et al. Among authors: gronbaek k. Anal Chem. 2018 Dec 18;90(24):14198-14206. doi: 10.1021/acs.analchem.8b02910. Epub 2018 Dec 4. Anal Chem. 2018. PMID: 30422637 Free PMC article.
Oral vitamin C supplementation to patients with myeloid cancer on azacitidine treatment: Normalization of plasma vitamin C induces epigenetic changes.
Gillberg L, Ørskov AD, Nasif A, Ohtani H, Madaj Z, Hansen JW, Rapin N, Mogensen JB, Liu M, Dufva IH, Lykkesfeldt J, Hajkova P, Jones PA, Grønbæk K. Gillberg L, et al. Among authors: gronbaek k. Clin Epigenetics. 2019 Oct 17;11(1):143. doi: 10.1186/s13148-019-0739-5. Clin Epigenetics. 2019. PMID: 31623675 Free PMC article. Clinical Trial.
Activation of a Subset of Evolutionarily Young Transposable Elements and Innate Immunity Are Linked to Clinical Responses to 5-Azacytidine.
Ohtani H, Ørskov AD, Helbo AS, Gillberg L, Liu M, Zhou W, Ungerstedt J, Hellström-Lindberg E, Sun W, Liang G, Jones PA, Grønbæk K. Ohtani H, et al. Among authors: gronbaek k. Cancer Res. 2020 Jun 15;80(12):2441-2450. doi: 10.1158/0008-5472.CAN-19-1696. Epub 2020 Apr 3. Cancer Res. 2020. PMID: 32245794 Free PMC article.
The Thioredoxin-Interacting Protein TXNIP Is a Putative Tumour Suppressor in Cutaneous T-Cell Lymphoma.
Stolearenco V, Levring TB, Nielsen HM, Lindahl L, Fredholm S, Kongsbak-Wismann M, Willerslev-Olsen A, Buus TB, Nastasi C, Hu T, Gluud M, Côme CRM, Krejsgaard T, Iversen L, Bonefeld CM, Grønbæk K, Met Ö, Woetmann A, Ødum N, Geisler C. Stolearenco V, et al. Among authors: gronbaek k. Dermatology. 2021;237(2):283-290. doi: 10.1159/000509159. Epub 2020 Aug 14. Dermatology. 2021. PMID: 32799209
The role of vitamin C in epigenetic cancer therapy.
Mikkelsen SU, Gillberg L, Lykkesfeldt J, Grønbæk K. Mikkelsen SU, et al. Among authors: gronbaek k. Free Radic Biol Med. 2021 Jul;170:179-193. doi: 10.1016/j.freeradbiomed.2021.03.017. Epub 2021 Mar 28. Free Radic Biol Med. 2021. PMID: 33789122 Review.
226 results