Gilmore TD - Search Results

1

A conserved core region of the scaffold NEMO is essential for signal-induced conformational change and liquid-liquid phase separation.

DiRusso CJ, DeMaria AM, Wong J, Wang W, Jordanides JJ, Whitty A, Allen KN, Gilmore TD. DiRusso CJ, et al. Among authors: gilmore td. J Biol Chem. 2023 Dec;299(12):105396. doi: 10.1016/j.jbc.2023.105396. Epub 2023 Oct 27. J Biol Chem. 2023. PMID: 37890781 Free PMC article.

2

Phosphorylation of IkappaB-alpha inhibits its cleavage by caspase CPP32 in vitro.

Barkett M, Xue D, Horvitz HR, Gilmore TD. Barkett M, et al. Among authors: gilmore td. J Biol Chem. 1997 Nov 21;272(47):29419-22. doi: 10.1074/jbc.272.47.29419. J Biol Chem. 1997. PMID: 9367996 Free article.

3

Mutation of nonessential cysteines shows that the NF-κB essential modulator forms a constitutive noncovalent dimer that binds IκB kinase-β with high affinity.

Cote SM, Gilmore TD, Shaffer R, Weber U, Bollam R, Golden MS, Glover K, Herscovitch M, Ennis T, Allen KN, Whitty A. Cote SM, et al. Among authors: gilmore td. Biochemistry. 2013 Dec 23;52(51):9141-54. doi: 10.1021/bi401368r. Epub 2013 Dec 10. Biochemistry. 2013. PMID: 24266532 Free PMC article.

4

Disulfide-mediated stabilization of the IκB kinase binding domain of NF-κB essential modulator (NEMO).

Zhou L, Yeo AT, Ballarano C, Weber U, Allen KN, Gilmore TD, Whitty A. Zhou L, et al. Among authors: gilmore td. Biochemistry. 2014 Dec 23;53(50):7929-44. doi: 10.1021/bi500920n. Epub 2014 Dec 8. Biochemistry. 2014. PMID: 25400026 Free PMC article.

5

Inhibition of Oncogenic Transcription Factor REL by the Natural Product Derivative Calafianin Monomer 101 Induces Proliferation Arrest and Apoptosis in Human B-Lymphoma Cell Lines.

Yeo AT, Chennamadhavuni S, Whitty A, Porco JA Jr, Gilmore TD. Yeo AT, et al. Among authors: gilmore td. Molecules. 2015 Apr 23;20(5):7474-94. doi: 10.3390/molecules20057474. Molecules. 2015. PMID: 25915462 Free PMC article.

6

A Central Region of NF-κB Essential Modulator Is Required for IKKβ-Induced Conformational Change and for Signal Propagation.

Shaffer R, DeMaria AM, Kagermazova L, Liu Y, Babaei M, Caban-Penix S, Cervantes A, Jehle S, Makowski L, Gilmore TD, Whitty A, Allen KN. Shaffer R, et al. Among authors: gilmore td. Biochemistry. 2019 Jul 2;58(26):2906-2920. doi: 10.1021/acs.biochem.8b01316. Epub 2019 Jun 18. Biochemistry. 2019. PMID: 31145594 Free PMC article.

7

CRISPR/Cas9-based editing of a sensitive transcriptional regulatory element to achieve cell type-specific knockdown of the NEMO scaffold protein.

Babaei M, Liu Y, Wuerzberger-Davis SM, McCaslin EZ, DiRusso CJ, Yeo AT, Kagermazova L, Miyamoto S, Gilmore TD. Babaei M, et al. Among authors: gilmore td. PLoS One. 2019 Sep 25;14(9):e0222588. doi: 10.1371/journal.pone.0222588. eCollection 2019. PLoS One. 2019. PMID: 31553754 Free PMC article.

8

Comparison of NF-κB from the protists Capsaspora owczarzaki and Acanthoeca spectabilis reveals extensive evolutionary diversification of this transcription factor.

Williams LM, Sridhar S, Samaroo J, Peart J, Adindu EK, Addanki A, DiRusso CJ; BB522 Molecular Biology Laboratory; Aguirre Carrión PJ, Rodriguez-Sastre N, Siggers T, Gilmore TD. Williams LM, et al. Among authors: gilmore td. Commun Biol. 2021 Dec 16;4(1):1404. doi: 10.1038/s42003-021-02924-2. Commun Biol. 2021. PMID: 34916615 Free PMC article.

9

Scaffold proteins as dynamic integrators of biological processes.

DiRusso CJ, Dashtiahangar M, Gilmore TD. DiRusso CJ, et al. Among authors: gilmore td. J Biol Chem. 2022 Dec;298(12):102628. doi: 10.1016/j.jbc.2022.102628. Epub 2022 Oct 20. J Biol Chem. 2022. PMID: 36273588 Free PMC article. Review.

10

A Conserved Core Region of the Scaffold NEMO is Essential for Signal-induced Conformational Change and Liquid-liquid Phase Separation.

DiRusso CJ, DeMaria AM, Wong J, Jordanides JJ, Whitty A, Allen KN, Gilmore TD. DiRusso CJ, et al. Among authors: gilmore td. bioRxiv [Preprint]. 2023 May 25:2023.05.25.542299. doi: 10.1101/2023.05.25.542299. bioRxiv. 2023. PMID: 37292615 Free PMC article. Updated. Preprint.

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