Maechler P - Search Results

1

Screening for new inhibitors of the human Mitochondrial Pyruvate Carrier and their effects on hepatic glucose production and diabetes.

Herzig S, Li L, Jiménez-Sánchez C, Martinou JC, Maechler P. Herzig S, et al. Among authors: maechler p. Biochim Biophys Acta Gen Subj. 2023 Dec;1867(12):130492. doi: 10.1016/j.bbagen.2023.130492. Epub 2023 Oct 21. Biochim Biophys Acta Gen Subj. 2023. PMID: 37871770

2

Channels and transporters in cell metabolism.

Sonveaux P, Maechler P, Martinou JC. Sonveaux P, et al. Among authors: maechler p. Biochim Biophys Acta. 2016 Oct;1863(10):2359-61. doi: 10.1016/j.bbamcr.2016.06.001. Epub 2016 Jun 3. Biochim Biophys Acta. 2016. PMID: 27263487 Free article. No abstract available.

3

In vivo stabilization of OPA1 in hepatocytes potentiates mitochondrial respiration and gluconeogenesis in a prohibitin-dependent way.

Li L, Martin-Levilain J, Jiménez-Sánchez C, Karaca M, Foti M, Martinou JC, Maechler P. Li L, et al. Among authors: maechler p. J Biol Chem. 2019 Aug 23;294(34):12581-12598. doi: 10.1074/jbc.RA119.007601. Epub 2019 Jul 8. J Biol Chem. 2019. PMID: 31285263 Free PMC article.

4

Mitochondrial Carriers Regulating Insulin Secretion Profiled in Human Islets upon Metabolic Stress.

Jimenez-Sánchez C, Brun T, Maechler P. Jimenez-Sánchez C, et al. Among authors: maechler p. Biomolecules. 2020 Nov 12;10(11):1543. doi: 10.3390/biom10111543. Biomolecules. 2020. PMID: 33198243 Free PMC article.

5

Preventing mitochondrial fission impairs mitochondrial function and leads to loss of mitochondrial DNA.

Parone PA, Da Cruz S, Tondera D, Mattenberger Y, James DI, Maechler P, Barja F, Martinou JC. Parone PA, et al. Among authors: maechler p. PLoS One. 2008 Sep 22;3(9):e3257. doi: 10.1371/journal.pone.0003257. PLoS One. 2008. PMID: 18806874 Free PMC article.

6

Circulating 1,5-Anhydroglucitol as a Biomarker of ß-cell Mass Independent of a Diabetes Phenotype in Human Subjects.

Jiménez-Sánchez C, Mezza T, Sinturel F, Li L, Di Giuseppe G, Quero G, Jornayvaz FR, Guessous I, Dibner C, Schrauwen P, Alfieri S, Giaccari A, Maechler P. Jiménez-Sánchez C, et al. Among authors: maechler p. J Clin Endocrinol Metab. 2022 Sep 28;107(10):2833-2843. doi: 10.1210/clinem/dgac444. J Clin Endocrinol Metab. 2022. PMID: 35867405

7

Reply to Mishra: Prohibitin heterodimers-a complex time dependence for carcinogenesis.

Martin-Levilain J, Li L, Maechler P. Martin-Levilain J, et al. Among authors: maechler p. J Biol Chem. 2019 Oct 4;294(40):14837. doi: 10.1074/jbc.RL119.010819. J Biol Chem. 2019. PMID: 31586027 Free PMC article. No abstract available.

8

AMPK Profiling in Rodent and Human Pancreatic Beta-Cells under Nutrient-Rich Metabolic Stress.

Brun T, Jiménez-Sánchez C, Madsen JGS, Hadadi N, Duhamel D, Bartley C, Oberhauser L, Trajkovski M, Mandrup S, Maechler P. Brun T, et al. Among authors: maechler p. Int J Mol Sci. 2020 Jun 1;21(11):3982. doi: 10.3390/ijms21113982. Int J Mol Sci. 2020. PMID: 32492936 Free PMC article.

9

Glucolipotoxicity promotes the capacity of the glycerolipid/NEFA cycle supporting the secretory response of pancreatic beta cells.

Oberhauser L, Jiménez-Sánchez C, Madsen JGS, Duhamel D, Mandrup S, Brun T, Maechler P. Oberhauser L, et al. Among authors: maechler p. Diabetologia. 2022 Apr;65(4):705-720. doi: 10.1007/s00125-021-05633-x. Epub 2022 Jan 12. Diabetologia. 2022. PMID: 35018486

10

Lysophosphatidylinositols Are Upregulated After Human β-Cell Loss and Potentiate Insulin Release.

Jiménez-Sánchez C, Sinturel F, Mezza T, Loizides-Mangold U, Montoya JP, Li L, Di Giuseppe G, Quero G, Guessous I, Jornayvaz F, Schrauwen P, Stenvers DJ, Alfieri S, Giaccari A, Berishvili E, Compagnon P, Bosco D, Riezman H, Dibner C, Maechler P. Jiménez-Sánchez C, et al. Among authors: maechler p. Diabetes. 2024 Jan 1;73(1):93-107. doi: 10.2337/db23-0205. Diabetes. 2024. PMID: 37862465

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