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Development of Melanocortin 4 Receptor Agonists by Exploiting Animal-Derived Macrocyclic, Disulfide-Rich Peptide Scaffolds.
Muratspahić E, Aslanoglou D, White AM, Draxler C, Kozisek X, Farooq Z, Craik DJ, McCormick PJ, Durek T, Gruber CW. Muratspahić E, et al. Among authors: white am. ACS Pharmacol Transl Sci. 2023 Sep 26;6(10):1373-1381. doi: 10.1021/acsptsci.3c00090. eCollection 2023 Oct 13. ACS Pharmacol Transl Sci. 2023. PMID: 37854631 Free article.
Discovery and optimization of peptide macrocycles.
White AM, Craik DJ. White AM, et al. Expert Opin Drug Discov. 2016 Dec;11(12):1151-1163. doi: 10.1080/17460441.2016.1245720. Epub 2016 Oct 16. Expert Opin Drug Discov. 2016. PMID: 27718641 Review.
Melanocortin 1 Receptor Agonists Based on a Bivalent, Bicyclic Peptide Framework.
Durek T, Kaas Q, White AM, Weidmann J, Fuaad AA, Cheneval O, Schroeder CI, de Veer SJ, Dellsén A, Österlund T, Larsson N, Knerr L, Bauer U, Plowright AT, Craik DJ. Durek T, et al. Among authors: white am. J Med Chem. 2021 Jul 22;64(14):9906-9915. doi: 10.1021/acs.jmedchem.1c00095. Epub 2021 Jul 1. J Med Chem. 2021. PMID: 34197114
Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1.
Durek T, Cromm PM, White AM, Schroeder CI, Kaas Q, Weidmann J, Ahmad Fuaad A, Cheneval O, Harvey PJ, Daly NL, Zhou Y, Dellsén A, Österlund T, Larsson N, Knerr L, Bauer U, Kessler H, Cai M, Hruby VJ, Plowright AT, Craik DJ. Durek T, et al. Among authors: white am. J Med Chem. 2018 Apr 26;61(8):3674-3684. doi: 10.1021/acs.jmedchem.8b00170. Epub 2018 Apr 11. J Med Chem. 2018. PMID: 29605997 Free PMC article.
349 results