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TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression.
Heyes E, Wilhelmson AS, Wenzel A, Manhart G, Eder T, Schuster MB, Rzepa E, Pundhir S, D'Altri T, Frank AK, Gentil C, Woessmann J, Schoof EM, Meggendorfer M, Schwaller J, Haferlach T, Grebien F, Porse BT. Heyes E, et al. Among authors: porse bt. Nat Commun. 2023 Oct 4;14(1):6185. doi: 10.1038/s41467-023-41927-x. Nat Commun. 2023. PMID: 37794021 Free PMC article.
Exploration of cell state heterogeneity using single-cell proteomics through sensitivity-tailored data-independent acquisition.
Petrosius V, Aragon-Fernandez P, Üresin N, Kovacs G, Phlairaharn T, Furtwängler B, Op De Beeck J, Skovbakke SL, Goletz S, Thomsen SF, Keller UAD, Natarajan KN, Porse BT, Schoof EM. Petrosius V, et al. Among authors: porse bt. Nat Commun. 2023 Sep 22;14(1):5910. doi: 10.1038/s41467-023-41602-1. Nat Commun. 2023. PMID: 37737208 Free PMC article.
The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes.
Trempenau ML, Schuster MB, Pundhir S, Pereira MA, Kalvisa A, Tapia M, Su J, Ge Y, de Boer B, Balhuizen A, Bagger FO, Shliaha P, Sroczynska P, Walfridsson J, Grønbæk K, Theilgaard-Mönch K, Jensen ON, Helin K, Porse BT. Trempenau ML, et al. Among authors: porse bt. Leukemia. 2023 Mar;37(3):593-605. doi: 10.1038/s41375-023-01810-6. Epub 2023 Jan 12. Leukemia. 2023. PMID: 36631623 Free PMC article.
Engineering human mini-bones for the standardized modeling of healthy hematopoiesis, leukemia, and solid tumor metastasis.
Grigoryan A, Zacharaki D, Balhuizen A, Côme CR, Garcia AG, Hidalgo Gil D, Frank AK, Aaltonen K, Mañas A, Esfandyari J, Kjellman P, Englund E, Rodriguez C, Sime W, Massoumi R, Kalantari N, Prithiviraj S, Li Y, Dupard SJ, Isaksson H, Madsen CD, Porse BT, Bexell D, Bourgine PE. Grigoryan A, et al. Among authors: porse bt. Sci Transl Med. 2022 Oct 12;14(666):eabm6391. doi: 10.1126/scitranslmed.abm6391. Epub 2022 Oct 12. Sci Transl Med. 2022. PMID: 36223446
94 results