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Page 1
Finding synergies for the 3Rs - Repeated Dose Toxicity testing: Report from an EPAA Partners' Forum.
Laroche C, Annys E, Bender H, Botelho D, Botham P, Brendler-Schwaab S, Clayton R, Corvaro M, Dal Negro G, Delannois F, Dent M, Desaintes C, Desprez B, Dhalluin S, Hartmann A, Hoffmann-Doerr S, Hubesch B, Irizar A, Manou I, Müller BP, Nadzialek S, Prieto P, Rasenberg M, Roggeband R, Rowan TG, Schutte K, van de Water B, Westmoreland C, Whelan M, Wilschut A, Zvonimir Z, Cronin MTD. Laroche C, et al. Among authors: manou i. Regul Toxicol Pharmacol. 2019 Nov;108:104470. doi: 10.1016/j.yrtph.2019.104470. Epub 2019 Aug 31. Regul Toxicol Pharmacol. 2019. PMID: 31479718 Free article.
New ideas for non-animal approaches to predict repeated-dose systemic toxicity: Report from an EPAA Blue Sky Workshop.
Mahony C, Ashton RS, Birk B, Boobis AR, Cull T, Daston GP, Ewart L, Knudsen TB, Manou I, Maurer-Stroh S, Margiotta-Casaluci L, Müller BP, Nordlund P, Roberts RA, Steger-Hartmann T, Vandenbossche E, Viant MR, Vinken M, Whelan M, Zvonimir Z, Cronin MTD. Mahony C, et al. Among authors: manou i. Regul Toxicol Pharmacol. 2020 Jul;114:104668. doi: 10.1016/j.yrtph.2020.104668. Epub 2020 Apr 23. Regul Toxicol Pharmacol. 2020. PMID: 32335207 Free article.
Building confidence in skin sensitisation potency assessment using new approach methodologies: report of the 3rd EPAA Partners Forum, Brussels, 28th October 2019.
Basketter D, Beken S, Bender H, Bridges J, Casati S, Corvaro M, Cuvellier S, Hubesch B, Irizar A, Jacobs MN, Kern P, Lamplmair F, Manou I, Müller BP, Roggeband R, Rossi LH. Basketter D, et al. Among authors: manou i. Regul Toxicol Pharmacol. 2020 Nov;117:104767. doi: 10.1016/j.yrtph.2020.104767. Epub 2020 Aug 28. Regul Toxicol Pharmacol. 2020. PMID: 32866543 Free article. Review.
A comprehensive view on mechanistic approaches for cancer risk assessment of non-genotoxic agrochemicals.
Luijten M, Corvi R, Mehta J, Corvaro M, Delrue N, Felter S, Haas B, Hewitt NJ, Hilton G, Holmes T, Jacobs MN, Jacobs A, Lamplmair F, Lewis D, Madia F, Manou I, Melching-Kollmuss S, Schorsch F, Schütte K, Sewell F, Strupp C, van der Laan JW, Wolf DC, Wolterink G, Woutersen R, Zvonar Z, Heusinkveld H, Braakhuis H. Luijten M, et al. Among authors: manou i. Regul Toxicol Pharmacol. 2020 Dec;118:104789. doi: 10.1016/j.yrtph.2020.104789. Epub 2020 Oct 7. Regul Toxicol Pharmacol. 2020. PMID: 33035627 Free article. Review.
Finding synergies for 3Rs - Toxicokinetics and read-across: Report from an EPAA partners' Forum.
Laroche C, Aggarwal M, Bender H, Benndorf P, Birk B, Crozier J, Dal Negro G, De Gaetano F, Desaintes C, Gardner I, Hubesch B, Irizar A, John D, Kumar V, Lostia A, Manou I, Monshouwer M, Müller BP, Paini A, Reid K, Rowan T, Sachana M, Schutte K, Stirling C, Taalman R, van Aerts L, Weissenhorn R, Sauer UG. Laroche C, et al. Among authors: manou i. Regul Toxicol Pharmacol. 2018 Nov;99:5-21. doi: 10.1016/j.yrtph.2018.08.006. Epub 2018 Aug 23. Regul Toxicol Pharmacol. 2018. PMID: 30144470 Free article.
In vitro RHE skin sensitisation assays: Applicability to challenging substances.
Mehling A, Adriaens E, Casati S, Hubesch B, Irizar A, Klaric M, Letasiova S, Manou I, Müller BP, Roggen E, van Vliet E, Basketter D. Mehling A, et al. Among authors: manou i. Regul Toxicol Pharmacol. 2019 Nov;108:104473. doi: 10.1016/j.yrtph.2019.104473. Epub 2019 Sep 5. Regul Toxicol Pharmacol. 2019. PMID: 31494190 Free article.
Applying non-animal strategies for assessing skin sensitisation report from an EPAA/cefic-LRI/IFRA Europe cross sector workshop, ECHA helsinki, February 7th and 8th 2019.
Basketter D, Azam P, Casati S, Corvaro M, Ezendam J, Griem P, Hubesch B, Irizar A, Kern P, Manou I, Mehling A, Rossi LH. Basketter D, et al. Among authors: manou i. Regul Toxicol Pharmacol. 2019 Dec;109:104477. doi: 10.1016/j.yrtph.2019.104477. Epub 2019 Oct 3. Regul Toxicol Pharmacol. 2019. PMID: 31586681 Free article.
One science-driven approach for the regulatory implementation of alternative methods: A multi-sector perspective.
Dal Negro G, Eskes C, Belz S, Bertein C, Chlebus M, Corvaro M, Corvi R, Dhalluin S, Halder M, Harvey J, Hermann M, Hoffmann-Dörr S, Kilian K, Lambrigts D, Laroche C, Louhimies S, Mahony C, Manou I, McNamee P, Prieto P, Reid K, Roggen E, Schutte K, Stirling C, Uhlrich S, Weissenhorn R, Whelan M. Dal Negro G, et al. Among authors: manou i. Regul Toxicol Pharmacol. 2018 Nov;99:33-49. doi: 10.1016/j.yrtph.2018.08.002. Epub 2018 Aug 8. Regul Toxicol Pharmacol. 2018. PMID: 30098372 Free article.
Towards a mechanism-based approach for the prediction of nongenotoxic carcinogenic potential of agrochemicals.
Heusinkveld H, Braakhuis H, Gommans R, Botham P, Corvaro M, van der Laan JW, Lewis D, Madia F, Manou I, Schorsch F, Wolterink G, Woutersen R, Corvi R, Mehta J, Luijten M. Heusinkveld H, et al. Among authors: manou i. Crit Rev Toxicol. 2020 Oct;50(9):725-739. doi: 10.1080/10408444.2020.1841732. Epub 2020 Nov 25. Crit Rev Toxicol. 2020. PMID: 33236972 Review.
30 results