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Rare antibody phage isolation and discrimination (RAPID) biopanning enables identification of high-affinity antibodies against challenging targets.
Commun Biol. 2023 Oct 12;6(1):1036. doi: 10.1038/s42003-023-05390-0.
Commun Biol. 2023.
PMID: 37828150
Free PMC article.
The E3 Ubiquitin Ligase, CHIP/STUB1, Inhibits Aggregation of Phosphorylated Proteoforms of Microtubule-associated Protein Tau (MAPT).
Nadel CM, Thwin AC, Callahan M, Lee K, Connelly E, Craik CS, Southworth DR, Gestwicki JE.
Nadel CM, et al.
J Mol Biol. 2023 Jun 1;435(11):168026. doi: 10.1016/j.jmb.2023.168026. Epub 2023 Jun 16.
J Mol Biol. 2023.
PMID: 37330289
Free PMC article.
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Inhibiting a dynamic viral protease by targeting a non-catalytic cysteine.
Hulce KR, Jaishankar P, Lee GM, Bohn MF, Connelly EJ, Wucherer K, Ongpipattanakul C, Volk RF, Chuo SW, Arkin MR, Renslo AR, Craik CS.
Hulce KR, et al. Among authors: connelly ej.
Cell Chem Biol. 2022 May 19;29(5):785-798.e19. doi: 10.1016/j.chembiol.2022.03.007. Epub 2022 Mar 31.
Cell Chem Biol. 2022.
PMID: 35364007
Free PMC article.
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Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia.
Asarnow D, Wang B, Lee WH, Hu Y, Huang CW, Faust B, Ng PML, Ngoh EZX, Bohn M, Bulkley D, Pizzorno A, Ary B, Tan HC, Lee CY, Minhat RA, Terrier O, Soh MK, Teo FJ, Yeap YYC, Seah SGK, Chan CEZ, Connelly E, Young NJ, Maurer-Stroh S, Renia L, Hanson BJ, Rosa-Calatrava M, Manglik A, Cheng Y, Craik CS, Wang CI.
Asarnow D, et al.
Cell. 2021 Jun 10;184(12):3192-3204.e16. doi: 10.1016/j.cell.2021.04.033. Epub 2021 Apr 24.
Cell. 2021.
PMID: 33974910
Free PMC article.
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