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Oncogenic context shapes the fitness landscape of tumor suppression.
Blair LM, Juan JM, Sebastian L, Tran VB, Nie W, Wall GD, Gerceker M, Lai IK, Apilado EA, Grenot G, Amar D, Foggetti G, Do Carmo M, Ugur Z, Deng D, Chenchik A, Paz Zafra M, Dow LE, Politi K, MacQuitty JJ, Petrov DA, Winslow MM, Rosen MJ, Winters IP. Blair LM, et al. Among authors: petrov da. Nat Commun. 2023 Oct 12;14(1):6422. doi: 10.1038/s41467-023-42156-y. Nat Commun. 2023. PMID: 37828026 Free PMC article.
Fully accessible fitness landscape of oncogene-negative lung adenocarcinoma.
Yousefi M, Andrejka L, Szamecz M, Winslow MM, Petrov DA, Boross G. Yousefi M, et al. Among authors: petrov da. Proc Natl Acad Sci U S A. 2023 Sep 19;120(38):e2303224120. doi: 10.1073/pnas.2303224120. Epub 2023 Sep 11. Proc Natl Acad Sci U S A. 2023. PMID: 37695905 Free PMC article.
Multiplexed screens identify RAS paralogues HRAS and NRAS as suppressors of KRAS-driven lung cancer growth.
Tang R, Shuldiner EG, Kelly M, Murray CW, Hebert JD, Andrejka L, Tsai MK, Hughes NW, Parker MI, Cai H, Li YC, Wahl GM, Dunbrack RL, Jackson PK, Petrov DA, Winslow MM. Tang R, et al. Among authors: petrov da. Nat Cell Biol. 2023 Jan;25(1):159-169. doi: 10.1038/s41556-022-01049-w. Epub 2023 Jan 12. Nat Cell Biol. 2023. PMID: 36635501 Free PMC article.
A multiplexed in vivo approach to identify driver genes in small cell lung cancer.
Lee MC, Cai H, Murray CW, Li C, Shue YT, Andrejka L, He AL, Holzem AME, Drainas AP, Ko JH, Coles GL, Kong C, Zhu S, Zhu C, Wang J, van de Rijn M, Petrov DA, Winslow MM, Sage J. Lee MC, et al. Among authors: petrov da. Cell Rep. 2023 Jan 31;42(1):111990. doi: 10.1016/j.celrep.2023.111990. Epub 2023 Jan 13. Cell Rep. 2023. PMID: 36640300 Free PMC article.
Author Correction: Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia.
Zhu X, Zhou B, Pattni R, Gleason K, Tan C, Kalinowski A, Sloan S, Fiston-Lavier AS, Mariani J, Petrov D, Barres BA, Duncan L, Abyzov A, Vogel H; Brain Somatic Mosaicism Network; Moran JV, Vaccarino FM, Tamminga CA, Levinson DF, Urban AE. Zhu X, et al. Nat Neurosci. 2023 Oct;26(10):1833. doi: 10.1038/s41593-023-01438-w. Nat Neurosci. 2023. PMID: 37648813 No abstract available.
Modeling the genomic complexity of human cancer using Cas12a mice.
Hebert JD, Xu H, Tang YJ, Ruiz PA, Detrick C, Wang J, Hughes NW, Donosa O, Andrejka L, Karmakar S, Aboiralor I, Cong L, Sage J, Petrov DA, Winslow MM. Hebert JD, et al. Among authors: petrov da. bioRxiv [Preprint]. 2024 Mar 8:2024.03.07.583774. doi: 10.1101/2024.03.07.583774. bioRxiv. 2024. PMID: 38496463 Free PMC article. Preprint.
Single-fly assemblies fill major phylogenomic gaps across the Drosophilidae Tree of Life.
Kim BY, Gellert HR, Church SH, Suvorov A, Anderson SS, Barmina O, Beskid SG, Comeault AA, Crown KN, Diamond SE, Dorus S, Fujichika T, Hemker JA, Hrcek J, Kankare M, Katoh T, Magnacca KN, Martin RA, Matsunaga T, Medeiros MJ, Miller DE, Pitnick S, Simoni S, Steenwinkel TE, Schiffer M, Syed ZA, Takahashi A, Wei KH, Yokoyama T, Eisen MB, Kopp A, Matute D, Obbard DJ, O'Grady PM, Price DK, Toda MJ, Werner T, Petrov DA. Kim BY, et al. Among authors: petrov da. bioRxiv [Preprint]. 2023 Oct 2:2023.10.02.560517. doi: 10.1101/2023.10.02.560517. bioRxiv. 2023. PMID: 37873137 Free PMC article. Preprint.
185 results