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Probiotic-guided CAR-T cells for solid tumor targeting.
Vincent RL, Gurbatri CR, Li F, Vardoshvili A, Coker C, Im J, Ballister ER, Rouanne M, Savage T, de Los Santos-Alexis K, Redenti A, Brockmann L, Komaranchath M, Arpaia N, Danino T. Vincent RL, et al. Among authors: arpaia n. Science. 2023 Oct 13;382(6667):211-218. doi: 10.1126/science.add7034. Epub 2023 Oct 12. Science. 2023. PMID: 37824640
Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblasts.
Bhattacharjee S, Hamberger F, Ravichandra A, Miller M, Nair A, Affo S, Filliol A, Chin L, Savage TM, Yin D, Wirsik NM, Mehal A, Arpaia N, Seki E, Mack M, Zhu D, Sims PA, Kalluri R, Stanger BZ, Olive KP, Schmidt T, Wells RG, Mederacke I, Schwabe RF. Bhattacharjee S, et al. Among authors: arpaia n. J Clin Invest. 2021 Jun 1;131(11):e146987. doi: 10.1172/JCI146987. J Clin Invest. 2021. PMID: 33905375 Free PMC article.
The Origin and Contribution of Cancer-Associated Fibroblasts in Colorectal Carcinogenesis.
Kobayashi H, Gieniec KA, Lannagan TRM, Wang T, Asai N, Mizutani Y, Iida T, Ando R, Thomas EM, Sakai A, Suzuki N, Ichinose M, Wright JA, Vrbanac L, Ng JQ, Goyne J, Radford G, Lawrence MJ, Sammour T, Hayakawa Y, Klebe S, Shin AE, Asfaha S, Bettington ML, Rieder F, Arpaia N, Danino T, Butler LM, Burt AD, Leedham SJ, Rustgi AK, Mukherjee S, Takahashi M, Wang TC, Enomoto A, Woods SL, Worthley DL. Kobayashi H, et al. Among authors: arpaia n. Gastroenterology. 2022 Mar;162(3):890-906. doi: 10.1053/j.gastro.2021.11.037. Epub 2021 Dec 6. Gastroenterology. 2022. PMID: 34883119 Free PMC article.
A programmable encapsulation system improves delivery of therapeutic bacteria in mice.
Harimoto T, Hahn J, Chen YY, Im J, Zhang J, Hou N, Li F, Coker C, Gray K, Harr N, Chowdhury S, Pu K, Nimura C, Arpaia N, Leong KW, Danino T. Harimoto T, et al. Among authors: arpaia n. Nat Biotechnol. 2022 Aug;40(8):1259-1269. doi: 10.1038/s41587-022-01244-y. Epub 2022 Mar 17. Nat Biotechnol. 2022. PMID: 35301496 Free PMC article.
BCG therapy downregulates HLA-I on malignant cells to subvert antitumor immune responses in bladder cancer.
Rouanne M, Adam J, Radulescu C, Letourneur D, Bredel D, Mouraud S, Goubet AG, Leduc M, Chen N, Tan TZ, Signolle N, Bigorgne A, Dussiot M, Tselikas L, Susini S, Danlos FX, Schneider AK, Chabanon R, Vacher S, Bièche I, Lebret T, Allory Y, Soria JC, Arpaia N, Kroemer G, Kepp O, Thiery JP, Zitvogel L, Marabelle A. Rouanne M, et al. Among authors: arpaia n. J Clin Invest. 2022 Jun 15;132(12):e145666. doi: 10.1172/JCI145666. J Clin Invest. 2022. PMID: 35503263 Free PMC article.
Engineering bacteria as interactive cancer therapies.
Gurbatri CR, Arpaia N, Danino T. Gurbatri CR, et al. Among authors: arpaia n. Science. 2022 Nov 25;378(6622):858-864. doi: 10.1126/science.add9667. Epub 2022 Nov 24. Science. 2022. PMID: 36423303 Free PMC article. Review.
59 results