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Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD.
Cell Stem Cell. 2023 Oct 5;30(10):1299-1314.e9. doi: 10.1016/j.stem.2023.08.014.
Cell Stem Cell. 2023.
PMID: 37802036
Free article.
Grafts Derived from an α-Synuclein Triplication Patient Mediate Functional Recovery but Develop Disease-Associated Pathology in the 6-OHDA Model of Parkinson's Disease.
Shrigley S, Nilsson F, Mattsson B, Fiorenzano A, Mudannayake J, Bruzelius A, Ottosson DR, Björklund A, Hoban DB, Parmar M.
Shrigley S, et al. Among authors: mudannayake j.
J Parkinsons Dis. 2021;11(2):515-528. doi: 10.3233/JPD-202366.
J Parkinsons Dis. 2021.
PMID: 33361611
Free PMC article.
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A systematic capsid evolution approach performed in vivo for the design of AAV vectors with tailored properties and tropism.
Davidsson M, Wang G, Aldrin-Kirk P, Cardoso T, Nolbrant S, Hartnor M, Mudannayake J, Parmar M, Björklund T.
Davidsson M, et al. Among authors: mudannayake j.
Proc Natl Acad Sci U S A. 2019 Dec 26;116(52):27053-27062. doi: 10.1073/pnas.1910061116. Epub 2019 Dec 9.
Proc Natl Acad Sci U S A. 2019.
PMID: 31818949
Free PMC article.
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Monitoring the interactions between alpha-synuclein and Tau in vitro and in vivo using bimolecular fluorescence complementation.
Torres-Garcia L, P Domingues JM, Brandi E, Haikal C, Mudannayake JM, Brás IC, Gerhardt E, Li W, Svanbergsson A, Outeiro TF, Gouras GK, Li JY.
Torres-Garcia L, et al. Among authors: mudannayake jm.
Sci Rep. 2022 Feb 22;12(1):2987. doi: 10.1038/s41598-022-06846-9.
Sci Rep. 2022.
PMID: 35194057
Free PMC article.
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Transcriptional activity of novel ALDH1L1 promoters in the rat brain following AAV vector-mediated gene transfer.
Mudannayake JM, Mouravlev A, Fong DM, Young D.
Mudannayake JM, et al.
Mol Ther Methods Clin Dev. 2016 Nov 30;3:16075. doi: 10.1038/mtm.2016.75. eCollection 2016.
Mol Ther Methods Clin Dev. 2016.
PMID: 27990448
Free PMC article.
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