Oo A - Search Results

1

Gene editing of SAMHD1 in macrophage-like cells reveals complex relationships between SAMHD1 phospho-regulation, HIV-1 restriction, and cellular dNTP levels.

Schüssler M, Schott K, Fuchs NV, Oo A, Zahadi M, Rauch P, Kim B, König R. Schüssler M, et al. Among authors: oo a. mBio. 2023 Oct 31;14(5):e0225223. doi: 10.1128/mbio.02252-23. Epub 2023 Oct 6. mBio. 2023. PMID: 37800914 Free PMC article.

2

Viral protein X reduces the incorporation of mutagenic noncanonical rNTPs during lentivirus reverse transcription in macrophages.

Oo A, Kim DH, Schinazi RF, Kim B. Oo A, et al. J Biol Chem. 2020 Jan 10;295(2):657-666. doi: 10.1074/jbc.RA119.011466. Epub 2019 Dec 5. J Biol Chem. 2020. PMID: 31806704 Free PMC article.

3

Tetraspanin CD81 regulates HSV-1 infection.

Benayas B, Sastre I, López-Martín S, Oo A, Kim B, Bullido MJ, Aldudo J, Yáñez-Mó M. Benayas B, et al. Among authors: oo a. Med Microbiol Immunol. 2020 Aug;209(4):489-498. doi: 10.1007/s00430-020-00684-0. Epub 2020 Jun 4. Med Microbiol Immunol. 2020. PMID: 32500359 Free PMC article.

4

Repurposing Nucleoside Analogs for Human Coronaviruses.

Zandi K, Amblard F, Musall K, Downs-Bowen J, Kleinbard R, Oo A, Cao D, Liang B, Russell OO, McBrayer T, Bassit L, Kim B, Schinazi RF. Zandi K, et al. Among authors: oo a. Antimicrob Agents Chemother. 2020 Dec 16;65(1):e01652-20. doi: 10.1128/AAC.01652-20. Print 2020 Dec 16. Antimicrob Agents Chemother. 2020. PMID: 33122172 Free PMC article.

5

A highly potent and safe pyrrolopyridine-based allosteric HIV-1 integrase inhibitor targeting host LEDGF/p75-integrase interaction site.

Maehigashi T, Ahn S, Kim UI, Lindenberger J, Oo A, Koneru PC, Mahboubi B, Engelman AN, Kvaratskhelia M, Kim K, Kim B. Maehigashi T, et al. Among authors: oo a. PLoS Pathog. 2021 Jul 22;17(7):e1009671. doi: 10.1371/journal.ppat.1009671. eCollection 2021 Jul. PLoS Pathog. 2021. PMID: 34293041 Free PMC article.

6

Novel Insights into the Molecular Regulation of Ribonucleotide Reductase in Adrenocortical Carcinoma Treatment.

Bothou C, Sharma A, Oo A, Kim B, Perge P, Igaz P, Ronchi CL, Shapiro I, Hantel C. Bothou C, et al. Among authors: oo a. Cancers (Basel). 2021 Aug 20;13(16):4200. doi: 10.3390/cancers13164200. Cancers (Basel). 2021. PMID: 34439352 Free PMC article.

7

Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins.

Bowen NE, Temple J, Shepard C, Oo A, Arizaga F, Kapoor-Vazirani P, Persaud M, Yu CH, Kim DH, Schinazi RF, Ivanov DN, Diaz-Griffero F, Yu DS, Xiong Y, Kim B. Bowen NE, et al. Among authors: oo a. J Biol Chem. 2021 Oct;297(4):101170. doi: 10.1016/j.jbc.2021.101170. Epub 2021 Sep 4. J Biol Chem. 2021. PMID: 34492268 Free PMC article.

8

Elimination of Aicardi-Goutières syndrome protein SAMHD1 activates cellular innate immunity and suppresses SARS-CoV-2 replication.

Oo A, Zandi K, Shepard C, Bassit LC, Musall K, Goh SL, Cho YJ, Kim DH, Schinazi RF, Kim B. Oo A, et al. J Biol Chem. 2022 Mar;298(3):101635. doi: 10.1016/j.jbc.2022.101635. Epub 2022 Jan 25. J Biol Chem. 2022. PMID: 35085552 Free PMC article.

9

Mechanistic Interplay between HIV-1 Reverse Transcriptase Enzyme Kinetics and Host SAMHD1 Protein: Viral Myeloid-Cell Tropism and Genomic Mutagenesis.

Bowen NE, Oo A, Kim B. Bowen NE, et al. Among authors: oo a. Viruses. 2022 Jul 26;14(8):1622. doi: 10.3390/v14081622. Viruses. 2022. PMID: 35893688 Free PMC article. Review.

10

Gene editing of SAMHD1 in macrophage-like cells reveals complex relationships between SAMHD1 phospho-regulation, HIV-1 restriction and cellular dNTP levels.

Schüssler M, Schott K, Fuchs NV, Oo A, Zahadi M, Rauch P, Kim B, König R. Schüssler M, et al. Among authors: oo a. bioRxiv [Preprint]. 2023 Aug 25:2023.08.24.554731. doi: 10.1101/2023.08.24.554731. bioRxiv. 2023. PMID: 37662193 Free PMC article. Updated. Preprint.

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