Bignon J - Search Results

1

Structure-Based Design of a Lead Compound Derived from Natural Schweinfurthins with Antitumor Properties That Target Oxysterol-Binding Protein.

Jézéquel G, Rampal C, Guimard C, Kovacs D, Polidori J, Bigay J, Bignon J, Askenatzis L, Litaudon M, Pham VC, Huong DTM, Nguyen AL, Pruvost A, Virolle T, Mesmin B, Desrat S, Antonny B, Roussi F. Jézéquel G, et al. Among authors: bignon j. J Med Chem. 2023 Oct 26;66(20):14208-14220. doi: 10.1021/acs.jmedchem.3c01298. Epub 2023 Oct 5. J Med Chem. 2023. PMID: 37795600

2

New C5-alkylated indolobenzazepinones acting as inhibitors of tubulin polymerization: cytotoxic and antitumor activities.

Keller L, Beaumont S, Liu JM, Thoret S, Bignon JS, Wdzieczak-Bakala J, Dauban P, Dodd RH. Keller L, et al. Among authors: bignon js. J Med Chem. 2008 Jun 26;51(12):3414-21. doi: 10.1021/jm701466p. Epub 2008 May 27. J Med Chem. 2008. PMID: 18503262

3

Synthesis and biological evaluation of a new series of highly functionalized 7'-homo-anhydrovinblastine derivatives.

Gherbovet O, Coderch C, García Alvarez MC, Bignon J, Thoret S, Martin MT, Guéritte F, Gago F, Roussi F. Gherbovet O, et al. Among authors: bignon j. J Med Chem. 2013 Aug 8;56(15):6088-100. doi: 10.1021/jm4004347. Epub 2013 Jul 18. J Med Chem. 2013. PMID: 23822556

4

Discovery of azaisoerianin derivatives as potential antitumors agents.

Soussi MA, Provot O, Bernadat G, Bignon J, Wdzieczak-Bakala J, Desravines D, Dubois J, Brion JD, Messaoudi S, Alami M. Soussi MA, et al. Among authors: bignon j. Eur J Med Chem. 2014 May 6;78:178-89. doi: 10.1016/j.ejmech.2014.03.032. Epub 2014 Mar 13. Eur J Med Chem. 2014. PMID: 24681982

5

One-pot synthesis of vinca alkaloids-phomopsin hybrids.

Gherbovet O, Coderch C, García Alvarez MC, Bignon J, Thoret S, Guéritte F, Gago F, Roussi F. Gherbovet O, et al. Among authors: bignon j. J Med Chem. 2014 Jun 26;57(12):5470-6. doi: 10.1021/jm500530v. Epub 2014 Jun 10. J Med Chem. 2014. PMID: 24871162

6

Rapid synthesis of 4-arylchromenes from ortho-substituted alkynols: A versatile access to restricted isocombretastatin A-4 analogues as antitumor agents.

Renko D, Provot O, Rasolofonjatovo E, Bignon J, Rodrigo J, Dubois J, Brion JD, Hamze A, Alami M. Renko D, et al. Among authors: bignon j. Eur J Med Chem. 2015 Jan 27;90:834-44. doi: 10.1016/j.ejmech.2014.12.024. Epub 2014 Dec 15. Eur J Med Chem. 2015. PMID: 25528337

7

Synthesis and evaluation of hybrid molecules targeting the vinca domain of tubulin.

Gherbovet O, Sánchez-Murcia PA, García Alvarez MC, Bignon J, Thoret S, Gago F, Roussi F. Gherbovet O, et al. Among authors: bignon j. Org Biomol Chem. 2015 Mar 14;13(10):3144-54. doi: 10.1039/c4ob02114b. Org Biomol Chem. 2015. PMID: 25634805

8

Synthesis and biological evaluation of C-13' substituted 7'-homo-anhydrovinblastine derivatives.

Gherbovet O, La Spisa F, Thoret S, Alvarez MCG, Levaique H, Bignon J, Roussi F. Gherbovet O, et al. Among authors: bignon j. Bioorg Med Chem Lett. 2015 Apr 15;25(8):1771-1773. doi: 10.1016/j.bmcl.2015.02.045. Epub 2015 Mar 7. Bioorg Med Chem Lett. 2015. PMID: 25804719

9

Antibacterial Labdane Diterpenoids from Vitex vestita.

Corlay N, Lecsö-Bornet M, Leborgne E, Blanchard F, Cachet X, Bignon J, Roussi F, Butel MJ, Awang K, Litaudon M. Corlay N, et al. Among authors: bignon j. J Nat Prod. 2015 Jun 26;78(6):1348-56. doi: 10.1021/acs.jnatprod.5b00206. Epub 2015 Jun 2. J Nat Prod. 2015. PMID: 26034885

10

Anacardic Acids from Knema hookeriana as Modulators of Bcl-xL/Bak and Mcl-1/Bid Interactions.

Gény C, Rivière G, Bignon J, Birlirakis N, Guittet E, Awang K, Litaudon M, Roussi F, Dumontet V. Gény C, et al. Among authors: bignon j. J Nat Prod. 2016 Apr 22;79(4):838-44. doi: 10.1021/acs.jnatprod.5b00915. Epub 2016 Mar 23. J Nat Prod. 2016. PMID: 27008174

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