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Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance.
Wei P, Song G, Shi M, Zhou Y, Liu Y, Lei J, Chen P, Yin L. Wei P, et al. Among authors: shi m. FASEB J. 2018 Feb;32(2):1085-1098. doi: 10.1096/fj.201700705R. Epub 2018 Jan 3. FASEB J. 2018. PMID: 29079699
These data demonstrate the crucial role of the PEA- and lipid A-binding pockets and provide novel insights into the structure-based mechanisms, important drug-target hot spots, and a drug template for further drug development to combat the urgent, rising threat of MCR-1-mediated …
These data demonstrate the crucial role of the PEA- and lipid A-binding pockets and provide novel insights into the structure-based mechanis …
Synergistic effects of Smac mimetic APG-1387 with anti-PD-1 antibody are attributed to increased CD3 + NK1.1 + cell recruitment secondary to induction of cytokines from tumor cells.
Pan W, Luo Q, Liang E, Shi M, Sun J, Shen H, Lu Z, Zhang L, Yan X, Yuan L, Zhou S, Yi H, Zhai Y, Qiu MZ, Yang D. Pan W, et al. Among authors: shi m. Cancer Cell Int. 2024 May 24;24(1):181. doi: 10.1186/s12935-024-03373-7. Cancer Cell Int. 2024. PMID: 38790057 Free PMC article.
7,464 results