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The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function.
Vanderhaeghen T, Timmermans S, Eggermont M, Watts D, Vandewalle J, Wallaeys C, Nuyttens L, De Temmerman J, Hochepied T, Dewaele S, Berghe JV, Sanders N, Wielockx B, Beyaert R, Libert C. Vanderhaeghen T, et al. Among authors: dewaele s. Front Immunol. 2023 Mar 16;14:1124011. doi: 10.3389/fimmu.2023.1124011. eCollection 2023. Front Immunol. 2023. PMID: 37006237 Free PMC article.
Point mutation I634A in the glucocorticoid receptor causes embryonic lethality by reduced ligand binding.
Timmermans S, Verhoog NJD, Van Looveren K, Dewaele S, Hochepied T, Eggermont M, Gilbert B, Boerema-de Munck A, Vanderhaeghen T, Vanden Berghe J, Garcia Gonzalez N, Vandewalle J, Bloch Y, Provost M, Savvides SN, De Bosscher K, Declercq W, Rottier RJ, Louw A, Libert C. Timmermans S, et al. Among authors: dewaele s. J Biol Chem. 2022 Feb;298(2):101574. doi: 10.1016/j.jbc.2022.101574. Epub 2022 Jan 8. J Biol Chem. 2022. PMID: 35007536 Free PMC article.
Correction to: The long non-coding RNA SAMMSON is essential for uveal melanoma cell survival.
Dewaele S, Delhaye L, De Paepe B, de Bony EJ, De Wilde J, Vanderheyden K, Anckaert J, Yigit N, Nuytens J, Vanden Eynde E, Smet J, Verschoore M, Nemati F, Decaudin D, Rodrigues M, Zhao P, Jochemsen A, Leucci E, Vandesompele J, Van Dorpe J, Marine JC, Van Coster R, Eyckerman S, Mestdagh P. Dewaele S, et al. Oncogene. 2022 Jan;41(1):146. doi: 10.1038/s41388-021-02051-6. Oncogene. 2022. PMID: 34782722 Free PMC article. No abstract available.
Reprogramming of glucocorticoid receptor function by hypoxia.
Vanderhaeghen T, Timmermans S, Watts D, Paakinaho V, Eggermont M, Vandewalle J, Wallaeys C, Van Wyngene L, Van Looveren K, Nuyttens L, Dewaele S, Vanden Berghe J, Lemeire K, De Backer J, Dirkx L, Vanden Berghe W, Caljon G, Ghesquière B, De Bosscher K, Wielockx B, Palvimo JJ, Beyaert R, Libert C. Vanderhaeghen T, et al. Among authors: dewaele s. EMBO Rep. 2022 Jan 5;23(1):e53083. doi: 10.15252/embr.202153083. Epub 2021 Oct 26. EMBO Rep. 2022. PMID: 34699114 Free PMC article.
The long non-coding RNA SAMMSON is essential for uveal melanoma cell survival.
Dewaele S, Delhaye L, De Paepe B, de Bony EJ, De Wilde J, Vanderheyden K, Anckaert J, Yigit N, Nuytens J, Vanden Eynde E, Smet J, Verschoore M, Nemati F, Decaudin D, Rodrigues M, Zhao P, Jochemsen A, Leucci E, Vandesompele J, Van Dorpe J, Marine JC, Van Coster R, Eyckerman S, Mestdagh P. Dewaele S, et al. Oncogene. 2022 Jan;41(1):15-25. doi: 10.1038/s41388-021-02006-x. Epub 2021 Sep 10. Oncogene. 2022. PMID: 34508176 Free PMC article.
Non-nucleoside reverse transcriptase inhibitor-based combination antiretroviral therapy is associated with lower cell-associated HIV RNA and DNA levels compared to protease inhibitor-based therapy.
Pasternak AO, Vroom J, Kootstra NA, Wit FW, de Bruin M, De Francesco D, Bakker M, Sabin CA, Winston A, Prins JM, Reiss P, Berkhout B; Co-morBidity in Relation to Aids (COBRA) Collaboration. Pasternak AO, et al. Elife. 2021 Aug 13;10:e68174. doi: 10.7554/eLife.68174. Elife. 2021. PMID: 34387543 Free PMC article.
ZBTB32 performs crosstalk with the glucocorticoid receptor and is crucial in glucocorticoid responses to starvation.
Van Wyngene L, Vanderhaeghen T, Petta I, Timmermans S, Corbeels K, Van der Schueren B, Vandewalle J, Van Looveren K, Wallaeys C, Eggermont M, Dewaele S, Catrysse L, van Loo G, Beyaert R, Vangoitsenhoven R, Nakayama T, Tavernier J, De Bosscher K, Libert C. Van Wyngene L, et al. Among authors: dewaele s. iScience. 2021 Jun 28;24(7):102790. doi: 10.1016/j.isci.2021.102790. eCollection 2021 Jul 23. iScience. 2021. PMID: 34337361 Free PMC article.
46 results