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Targeting the TWEAK-Fn14 pathway prevents dysfunction in cardiac calcium handling after acute kidney injury.
Poveda J, González-Lafuente L, Vázquez-Sánchez S, Mercado-García E, Rodríguez-Sánchez E, García-Consuegra I, Sanz AB, Segura J, Fernández-Velasco M, Liaño F, Ruilope LM, Ruiz-Hurtado G. Poveda J, et al. Among authors: gonzalez lafuente l. J Pathol. 2023 Dec;261(4):427-441. doi: 10.1002/path.6200. Epub 2023 Sep 30. J Pathol. 2023. PMID: 37776271
Partial Genetic Deletion of Klotho Aggravates Cardiac Calcium Mishandling in Acute Kidney Injury.
González-Lafuente L, Navarro-García JA, Valero-Almazán Á, Rodríguez-Sánchez E, Vázquez-Sánchez S, Mercado-García E, Pineros P, Poveda J, Fernández-Velasco M, Kuro-O M, Ruilope LM, Ruiz-Hurtado G. González-Lafuente L, et al. Int J Mol Sci. 2023 Jan 10;24(2):1322. doi: 10.3390/ijms24021322. Int J Mol Sci. 2023. PMID: 36674838 Free PMC article.
Enhanced Klotho availability protects against cardiac dysfunction induced by uraemic cardiomyopathy by regulating Ca2+ handling.
Navarro-García JA, Rueda A, Romero-García T, Aceves-Ripoll J, Rodríguez-Sánchez E, González-Lafuente L, Zaragoza C, Fernández-Velasco M, Kuro-O M, Ruilope LM, Ruiz-Hurtado G. Navarro-García JA, et al. Br J Pharmacol. 2020 Oct;177(20):4701-4719. doi: 10.1111/bph.15235. Epub 2020 Sep 15. Br J Pharmacol. 2020. PMID: 32830863 Free PMC article.
Oxidized Low-Density Lipoprotein Associates with Ventricular Stress in Young Adults and Triggers Intracellular Ca2+ Alterations in Adult Ventricular Cardiomyocytes.
Rodríguez-Sánchez E, Navarro-García JA, González-Lafuente L, Aceves-Ripoll J, Vázquez-Sánchez S, Poveda J, Mercado-García E, Corbacho-Alonso N, Calvo-Bonacho E, Fernández-Velasco M, Álvarez-Llamas G, Barderas MG, Ruilope LM, Ruiz-Hurtado G. Rodríguez-Sánchez E, et al. Antioxidants (Basel). 2020 Dec 1;9(12):1213. doi: 10.3390/antiox9121213. Antioxidants (Basel). 2020. PMID: 33271910 Free PMC article.
An Overview of FGF-23 as a Novel Candidate Biomarker of Cardiovascular Risk.
Vázquez-Sánchez S, Poveda J, Navarro-García JA, González-Lafuente L, Rodríguez-Sánchez E, Ruilope LM, Ruiz-Hurtado G. Vázquez-Sánchez S, et al. Among authors: gonzalez lafuente l. Front Physiol. 2021 Mar 9;12:632260. doi: 10.3389/fphys.2021.632260. eCollection 2021. Front Physiol. 2021. PMID: 33767635 Free PMC article. Review.
Interplay between mineral bone disorder and cardiac damage in acute kidney injury: from Ca2+ mishandling and preventive role of Klotho in mice to its potential mortality prediction in human.
González-Lafuente L, Navarro-García JA, Rodríguez-Sánchez E, Aceves-Ripoll J, Poveda J, Vázquez-Sánchez S, Mercado-García E, Fernández-Velasco M, Kuro-O M, Liaño F, Ruilope LM, Ruiz-Hurtado G. González-Lafuente L, et al. Transl Res. 2022 May;243:60-77. doi: 10.1016/j.trsl.2022.01.002. Epub 2022 Jan 22. Transl Res. 2022. PMID: 35077866
The anti-aging factor Klotho protects against acquired long QT syndrome induced by uremia and promoted by fibroblast growth factor 23.
Navarro-García JA, Salguero-Bodes R, González-Lafuente L, Martín-Nunes L, Rodríguez-Sánchez E, Bada-Bosch T, Hernández E, Mérida-Herrero E, Praga M, Solís J, Arribas F, Bueno H, Kuro-O M, Fernández-Velasco M, Ruilope LM, Delgado C, Ruiz-Hurtado G. Navarro-García JA, et al. Among authors: gonzalez lafuente l. BMC Med. 2022 Jan 19;20(1):14. doi: 10.1186/s12916-021-02209-9. BMC Med. 2022. PMID: 35042527 Free PMC article.
33 results