Lepelletier Y - Search Results

1

Structure-activity relationship studies and biological properties evaluation of peptidic NRP-1 ligands: Investigation of N-terminal cysteine importance.

Puszko AK, Sosnowski P, Hermine O, Hopfgartner G, Lepelletier Y, Misicka A. Puszko AK, et al. Among authors: lepelletier y. Bioorg Med Chem. 2023 Oct 30;94:117482. doi: 10.1016/j.bmc.2023.117482. Epub 2023 Sep 22. Bioorg Med Chem. 2023. PMID: 37774449 Free article.

2

Urea moiety as amide bond mimetic in peptide-like inhibitors of VEGF-A₁₆₅/NRP-1 complex.

Puszko AK, Sosnowski P, Pułka-Ziach K, Hermine O, Hopfgartner G, Lepelletier Y, Misicka A. Puszko AK, et al. Among authors: lepelletier y. Bioorg Med Chem Lett. 2019 Sep 1;29(17):2493-2497. doi: 10.1016/j.bmcl.2019.07.016. Epub 2019 Jul 10. Bioorg Med Chem Lett. 2019. PMID: 31326342

3

Does Cysteine Rule (CysR) Complete the CendR Principle? Increase in Affinity of Peptide Ligands for NRP-1 Through the Presence of N-Terminal Cysteine.

Puszko AK, Sosnowski P, Raynaud F, Hermine O, Hopfgartner G, Lepelletier Y, Misicka A. Puszko AK, et al. Among authors: lepelletier y. Biomolecules. 2020 Mar 13;10(3):448. doi: 10.3390/biom10030448. Biomolecules. 2020. PMID: 32183142 Free PMC article.

4

Urea-Peptide Hybrids as VEGF-A₁₆₅/NRP-1 Complex Inhibitors with Improved Receptor Affinity and Biological Properties.

Puszko AK, Sosnowski P, Rignault-Bricard R, Hermine O, Hopfgartner G, Pułka-Ziach K, Lepelletier Y, Misicka A. Puszko AK, et al. Among authors: lepelletier y. Int J Mol Sci. 2020 Dec 23;22(1):72. doi: 10.3390/ijms22010072. Int J Mol Sci. 2020. PMID: 33374715 Free PMC article.

5

Synthesis and structure-activity relationship of non-peptidic antagonists of neuropilin-1 receptor.

Liu WQ, Megale V, Borriello L, Leforban B, Montès M, Goldwaser E, Gresh N, Piquemal JP, Hadj-Slimane R, Hermine O, Garbay C, Raynaud F, Lepelletier Y, Demange L. Liu WQ, et al. Among authors: lepelletier y. Bioorg Med Chem Lett. 2014 Sep 1;24(17):4254-9. doi: 10.1016/j.bmcl.2014.07.028. Epub 2014 Jul 17. Bioorg Med Chem Lett. 2014. PMID: 25091928

6

Neuropilin-1 peptide-like ligands with proline mimetics, tested using the improved chemiluminescence affinity detection method.

Puszko AK, Sosnowski P, Tymecka D, Raynaud F, Hermine O, Lepelletier Y, Misicka A. Puszko AK, et al. Among authors: lepelletier y. Medchemcomm. 2019 Jan 25;10(2):332-340. doi: 10.1039/c8md00537k. eCollection 2019 Feb 1. Medchemcomm. 2019. PMID: 30881620 Free PMC article.

7

Synthesis, 3D-structure and stability analyses of NRPa-308, a new promising anti-cancer agent.

Brachet E, Dumond A, Liu WQ, Fabre M, Selkti M, Raynaud F, Hermine O, Benhida R, Belmont P, Garbay C, Lepelletier Y, Ronco C, Pagès G, Demange L. Brachet E, et al. Among authors: lepelletier y. Bioorg Med Chem Lett. 2019 Dec 15;29(24):126710. doi: 10.1016/j.bmcl.2019.126710. Epub 2019 Oct 16. Bioorg Med Chem Lett. 2019. PMID: 31699610

8

Neuropilin 1 and Neuropilin 2 gene invalidation or pharmacological inhibition reveals their relevance for the treatment of metastatic renal cell carcinoma.

Dumond A, Brachet E, Durivault J, Vial V, Puszko AK, Lepelletier Y, Montemagno C, Pagnuzzi-Boncompagni M, Hermine O, Garbay C, Lagarde N, Montes M, Demange L, Grépin R, Pagès G. Dumond A, et al. Among authors: lepelletier y. J Exp Clin Cancer Res. 2021 Jan 18;40(1):33. doi: 10.1186/s13046-021-01832-x. J Exp Clin Cancer Res. 2021. PMID: 33461580 Free PMC article.

9

Structure-based discovery of a small non-peptidic Neuropilins antagonist exerting in vitro and in vivo anti-tumor activity on breast cancer model.

Borriello L, Montès M, Lepelletier Y, Leforban B, Liu WQ, Demange L, Delhomme B, Pavoni S, Jarray R, Boucher JL, Dufour S, Hermine O, Garbay C, Hadj-Slimane R, Raynaud F. Borriello L, et al. Among authors: lepelletier y. Cancer Lett. 2014 Jul 28;349(2):120-7. doi: 10.1016/j.canlet.2014.04.004. Epub 2014 Apr 19. Cancer Lett. 2014. PMID: 24752068

10

Disruption of phactr-1 pathway triggers pro-inflammatory and pro-atherogenic factors: New insights in atherosclerosis development.

Jarray R, Pavoni S, Borriello L, Allain B, Lopez N, Bianco S, Liu WQ, Biard D, Demange L, Hermine O, Garbay C, Raynaud F, Lepelletier Y. Jarray R, et al. Among authors: lepelletier y. Biochimie. 2015 Nov;118:151-61. doi: 10.1016/j.biochi.2015.09.008. Epub 2015 Sep 9. Biochimie. 2015. PMID: 26362351

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