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Selective modifications of lactose and N-acetyllactosamine with sulfate and aromatic bulky groups unveil unique structural insights in galectin-1-ligand recognition.
Massaro M, Cagnoni AJ, Medrano FJ, Pérez-Sáez JM, Abdullayev S, Belkhadem K, Mariño KV, Romero A, Roy R, Rabinovich GA. Massaro M, et al. Among authors: rabinovich ga. Bioorg Med Chem. 2023 Oct 30;94:117480. doi: 10.1016/j.bmc.2023.117480. Epub 2023 Sep 21. Bioorg Med Chem. 2023. PMID: 37774448 Free article.
mRNAs encoding IL-12 and a decoy-resistant variant of IL-18 synergize to engineer T cells for efficacious intratumoral adoptive immunotherapy.
Olivera I, Bolaños E, Gonzalez-Gomariz J, Hervas-Stubbs S, Mariño KV, Luri-Rey C, Etxeberria I, Cirella A, Egea J, Glez-Vaz J, Garasa S, Alvarez M, Eguren-Santamaria I, Guedan S, Sanmamed MF, Berraondo P, Rabinovich GA, Teijeira A, Melero I. Olivera I, et al. Among authors: rabinovich ga. Cell Rep Med. 2023 Mar 17;4(3):100978. doi: 10.1016/j.xcrm.2023.100978. Online ahead of print. Cell Rep Med. 2023. PMID: 36933554 Free PMC article.
Mannosylated glycans impair normal T-cell development by reprogramming commitment and repertoire diversity.
Vicente MM, Alves I, Fernandes Â, Dias AM, Santos-Pereira B, Pérez-Anton E, Santos S, Yang T, Correia A, Münster-Kühnel A, Almeida ARM, Ravens S, Rabinovich GA, Vilanova M, Sousa AE, Pinho SS. Vicente MM, et al. Among authors: rabinovich ga. Cell Mol Immunol. 2023 Aug;20(8):955-968. doi: 10.1038/s41423-023-01052-7. Epub 2023 Jun 21. Cell Mol Immunol. 2023. PMID: 37344746 Free PMC article.
Do galectins serve as soluble ligands for immune checkpoint receptors?
Torres NI, Baudou FG, Scheidegger MA, Dalotto-Moreno T, Rabinovich GA. Torres NI, et al. Among authors: rabinovich ga. J Immunother Cancer. 2024 Apr 9;12(4):e008984. doi: 10.1136/jitc-2024-008984. J Immunother Cancer. 2024. PMID: 38599662 Free PMC article. No abstract available.
Sex-dependent expression of galectin-1, a cardioprotective β-galactoside-binding lectin, in human calcific aortic stenosis.
Jover E, Martín-Núñez E, Garaikoetxea M, Matilla L, Blanco-Colio LM, Pérez-Sáez JM, Navarro A, Fernández-Celis A, Gainza A, Álvarez V, Sádaba R, Tamayo I, Rabinovich GA, Martín-Ventura JL, López-Andrés N. Jover E, et al. Among authors: rabinovich ga. FASEB J. 2024 Feb 15;38(3):e23447. doi: 10.1096/fj.202301832RR. FASEB J. 2024. PMID: 38329326
Anchoring immunosuppression to inflamed tissue.
Mariño KV, Blidner AG, Rabinovich GA. Mariño KV, et al. Among authors: rabinovich ga. Nat Biomed Eng. 2023 Sep;7(9):1060-1062. doi: 10.1038/s41551-023-01055-9. Nat Biomed Eng. 2023. PMID: 37353678 No abstract available.
322 results