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XBP1 promotes NRASG12D pre-B acute lymphoblastic leukaemia through IL-7 receptor signalling and provides a therapeutic vulnerability for oncogenic RAS.
Salimi A, Schemionek-Reinders M, Huber M, Vieri M, Patterson JB, Alten J, Brümmendorf TH, Kharabi Masouleh B, Appelmann I. Salimi A, et al. Among authors: alten j. J Cell Mol Med. 2023 Nov;27(21):3363-3377. doi: 10.1111/jcmm.17904. Epub 2023 Sep 27. J Cell Mol Med. 2023. PMID: 37753803 Free PMC article.
Monitoring of minimal residual disease after allogeneic stem-cell transplantation in relapsed childhood acute lymphoblastic leukemia allows for the identification of impending relapse: results of the ALL-BFM-SCT 2003 trial.
Bader P, Kreyenberg H, von Stackelberg A, Eckert C, Salzmann-Manrique E, Meisel R, Poetschger U, Stachel D, Schrappe M, Alten J, Schrauder A, Schulz A, Lang P, Müller I, Albert MH, Willasch AM, Klingebiel TE, Peters C. Bader P, et al. Among authors: alten j. J Clin Oncol. 2015 Apr 10;33(11):1275-84. doi: 10.1200/JCO.2014.58.4631. Epub 2015 Jan 20. J Clin Oncol. 2015. PMID: 25605857 Clinical Trial.
Predictive value of minimal residual disease in Philadelphia-chromosome-positive acute lymphoblastic leukemia treated with imatinib in the European intergroup study of post-induction treatment of Philadelphia-chromosome-positive acute lymphoblastic leukemia, based on immunoglobulin/T-cell receptor and BCR/ABL1 methodologies.
Cazzaniga G, De Lorenzo P, Alten J, Röttgers S, Hancock J, Saha V, Castor A, Madsen HO, Gandemer V, Cavé H, Leoni V, Köhler R, Ferrari GM, Bleckmann K, Pieters R, van der Velden V, Stary J, Zuna J, Escherich G, Stadt UZ, Aricò M, Conter V, Schrappe M, Valsecchi MG, Biondi A. Cazzaniga G, et al. Among authors: alten j. Haematologica. 2018 Jan;103(1):107-115. doi: 10.3324/haematol.2017.176917. Epub 2017 Oct 27. Haematologica. 2018. PMID: 29079599 Free PMC article.
Frequency and prognostic impact of PAX5 p.P80R in pediatric acute lymphoblastic leukemia patients treated on an AIEOP-BFM acute lymphoblastic leukemia protocol.
Jung M, Schieck M, Hofmann W, Tauscher M, Lentes J, Bergmann A, Stelter M, Möricke A, Alten J, Schlegelberger B, Schrappe M, Zimmermann M, Stanulla M, Cario G, Steinemann D. Jung M, et al. Among authors: alten j. Genes Chromosomes Cancer. 2020 Nov;59(11):667-671. doi: 10.1002/gcc.22882. Epub 2020 Jul 7. Genes Chromosomes Cancer. 2020. PMID: 32592278 Free PMC article.
Transcriptional and Mutational Profiling of B-Other Acute Lymphoblastic Leukemia for Improved Diagnostics.
Chouvarine P, Antić Ž, Lentes J, Schröder C, Alten J, Brüggemann M, Carrillo-de Santa Pau E, Illig T, Laguna T, Schewe D, Stanulla M, Tang M, Zimmermann M, Schrappe M, Schlegelberger B, Cario G, Bergmann AK. Chouvarine P, et al. Among authors: alten j. Cancers (Basel). 2021 Nov 12;13(22):5653. doi: 10.3390/cancers13225653. Cancers (Basel). 2021. PMID: 34830809 Free PMC article.
Chemotherapy-related hyperbilirubinemia in pediatric acute lymphoblastic leukemia: a genome-wide association study from the AIEOP-BFM ALL study group.
Junk SV, Schaeffeler E, Zimmermann M, Möricke A, Beier R, Schütte P, Fedders B, Alten J, Hinze L, Klein N, Kulozik A, Muckenthaler MU, Koehler R, Borkhardt A, Vijayakrishnan J, Ellinghaus D, Forster M, Franke A, Wintering A, Kratz CP, Schrappe M, Schwab M, Houlston RS, Cario G, Stanulla M. Junk SV, et al. Among authors: alten j. J Exp Clin Cancer Res. 2023 Jan 13;42(1):21. doi: 10.1186/s13046-022-02585-x. J Exp Clin Cancer Res. 2023. PMID: 36639636 Free PMC article.
Molecular characterization of acute lymphoblastic leukemia with high CRLF2 gene expression in childhood.
Schmäh J, Fedders B, Panzer-Grümayer R, Fischer S, Zimmermann M, Dagdan E, Bens S, Schewe D, Moericke A, Alten J, Bleckmann K, Siebert R, Schrappe M, Stanulla M, Cario G. Schmäh J, et al. Among authors: alten j. Pediatr Blood Cancer. 2017 Oct;64(10). doi: 10.1002/pbc.26539. Epub 2017 Apr 1. Pediatr Blood Cancer. 2017. PMID: 28371317 Clinical Trial.
An Fc-engineered CD19 antibody eradicates MRD in patient-derived MLL-rearranged acute lymphoblastic leukemia xenografts.
Schewe DM, Alsadeq A, Sattler C, Lenk L, Vogiatzi F, Cario G, Vieth S, Valerius T, Rosskopf S, Meyersieck F, Alten J, Schrappe M, Gramatzki M, Peipp M, Kellner C. Schewe DM, et al. Among authors: alten j. Blood. 2017 Sep 28;130(13):1543-1552. doi: 10.1182/blood-2017-01-764316. Epub 2017 Jul 11. Blood. 2017. PMID: 28698205 Free article.
Near-tetraploid T-cell acute lymphoblastic leukaemia in childhood: Results of the AIEOP-BFM ALL studies.
Ceppi F, Gotti G, Möricke A, Silvestri D, Poyer F, Lentes J, Bergmann A, Trka J, Alten J, Elitzur S, Barbaric D, Buldini B, Dell'Acqua F, Schumacher F, Casazza G, Tchinda J, Nebral K, Conter V, Attarbaschi A, Schrappe M. Ceppi F, et al. Among authors: alten j. Eur J Cancer. 2022 Nov;175:120-124. doi: 10.1016/j.ejca.2022.08.013. Epub 2022 Sep 13. Eur J Cancer. 2022. PMID: 36113241 Free article.
146 results