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Clonal Decomposition and DNA Replication States Defined by Scaled Single-Cell Genome Sequencing.
Laks E, McPherson A, Zahn H, Lai D, Steif A, Brimhall J, Biele J, Wang B, Masud T, Ting J, Grewal D, Nielsen C, Leung S, Bojilova V, Smith M, Golovko O, Poon S, Eirew P, Kabeer F, Ruiz de Algara T, Lee SR, Taghiyar MJ, Huebner C, Ngo J, Chan T, Vatrt-Watts S, Walters P, Abrar N, Chan S, Wiens M, Martin L, Scott RW, Underhill TM, Chavez E, Steidl C, Da Costa D, Ma Y, Coope RJN, Corbett R, Pleasance S, Moore R, Mungall AJ, Mar C, Cafferty F, Gelmon K, Chia S; CRUK IMAXT Grand Challenge Team; Marra MA, Hansen C, Shah SP, Aparicio S. Laks E, et al. Cell. 2019 Nov 14;179(5):1207-1221.e22. doi: 10.1016/j.cell.2019.10.026. Cell. 2019. PMID: 31730858 Free PMC article.
Landscapes of cellular phenotypic diversity in breast cancer xenografts and their impact on drug response.
Georgopoulou D, Callari M, Rueda OM, Shea A, Martin A, Giovannetti A, Qosaj F, Dariush A, Chin SF, Carnevalli LS, Provenzano E, Greenwood W, Lerda G, Esmaeilishirazifard E, O'Reilly M, Serra V, Bressan D; IMAXT Consortium; Mills GB, Ali HR, Cosulich SS, Hannon GJ, Bruna A, Caldas C. Georgopoulou D, et al. Among authors: bressan d. Nat Commun. 2021 Mar 31;12(1):1998. doi: 10.1038/s41467-021-22303-z. Nat Commun. 2021. PMID: 33790302 Free PMC article.
Genome wide screen of RNAi molecules against SARS-CoV-2 creates a broadly potent prophylaxis.
Yogev O, Weissbrod O, Battistoni G, Bressan D, Naamti A, Falciatori I, Berkyurek AC, Rasnic R, Hosmillo M, Ilan S, Grossman I, McCormick L, Honeycutt CC, Johnston T, Gagne M, Douek DC, Goodfellow I, Hannon GJ, Erlich Y. Yogev O, et al. Among authors: bressan d. bioRxiv [Preprint]. 2022 Apr 12:2022.04.12.488010. doi: 10.1101/2022.04.12.488010. bioRxiv. 2022. PMID: 35441162 Free PMC article. Updated. Preprint.
From a genome-wide screen of RNAi molecules against SARS-CoV-2 to a validated broad-spectrum and potent prophylaxis.
Yogev O, Weissbrod O, Battistoni G, Bressan D, Naamati A, Falciatori I, Berkyurek AC, Rasnic R, Izuagbe R, Hosmillo M, Ilan S, Grossman I, McCormick L, Honeycutt CC, Johnston T, Gagne M, Douek DC, Goodfellow I, Hannon GJ, Erlich Y. Yogev O, et al. Among authors: bressan d. Commun Biol. 2023 Mar 16;6(1):277. doi: 10.1038/s42003-023-04589-5. Commun Biol. 2023. PMID: 36928598 Free PMC article.
FOXC2 promotes vasculogenic mimicry and resistance to anti-angiogenic therapy.
Cannell IG, Sawicka K, Pearsall I, Wild SA, Deighton L, Pearsall SM, Lerda G, Joud F, Khan S, Bruna A, Simpson KL, Mulvey CM, Nugent F, Qosaj F, Bressan D; CRUK IMAXT Grand Challenge Team; Dive C, Caldas C, Hannon GJ. Cannell IG, et al. Among authors: bressan d. Cell Rep. 2023 Aug 29;42(8):112791. doi: 10.1016/j.celrep.2023.112791. Epub 2023 Jul 26. Cell Rep. 2023. PMID: 37499655 Free article.
The dawn of spatial omics.
Bressan D, Battistoni G, Hannon GJ. Bressan D, et al. Science. 2023 Aug 4;381(6657):eabq4964. doi: 10.1126/science.abq4964. Epub 2023 Aug 4. Science. 2023. PMID: 37535749 Free PMC article. Review.
Imaging and Molecular Annotation of Xenographs and Tumours (IMAXT): High throughput data and analysis infrastructure.
González-Solares EA, Dariush A, González-Fernández C, Küpcü Yoldaş A, Molaeinezhad A, Al Sa'd M, Smith L, Whitmarsh T, Millar N, Chornay N, Falciatori I, Fatemi A, Goodwin D, Kuett L, Mulvey CM, Páez Ribes M, Qosaj F, Roth A, Vázquez-García I, Watson SS, Windhager J, Aparicio S, Bodenmiller B, Boyden E, Caldas C, Harris O, Shah SP, Tavaré S; CRUK IMAXT Grand Challenge Team; Bressan D, Hannon GJ, Walton NA. González-Solares EA, et al. Among authors: bressan d. Biol Imaging. 2023 Apr 14;3:e11. doi: 10.1017/S2633903X23000090. eCollection 2023. Biol Imaging. 2023. PMID: 38487685 Free PMC article.
42 results