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Nuclear envelope disruption triggers hallmarks of aging in lung alveolar macrophages.
De Silva NS, Siewiera J, Alkhoury C, Nader GPF, Nadalin F, de Azevedo K, Couty M, Izquierdo HM, Bhargava A, Conrad C, Maurin M, Antoniadou K, Fouillade C, Londono-Vallejo A, Behrendt R, Bertotti K, Serdjebi C, Lanthiez F, Gallwitz L, Saftig P, Herrero-Fernández B, Saez A, González-Granado JM, van Niel G, Boissonnas A, Piel M, Manel N. De Silva NS, et al. Among authors: saftig p. Nat Aging. 2023 Oct;3(10):1251-1268. doi: 10.1038/s43587-023-00488-w. Epub 2023 Sep 18. Nat Aging. 2023. PMID: 37723209
MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes.
Jungnickel KEJ, Guelle O, Iguchi M, Dong W, Kotov V, Gabriel F, Debacker C, Dairou J, McCort-Tranchepain I, Laqtom NN, Chan SH, Ejima A, Sato K, Massa López D, Saftig P, Mehdipour AR, Abu-Remaileh M, Gasnier B, Löw C, Damme M. Jungnickel KEJ, et al. Among authors: saftig p. Nat Cell Biol. 2024 Jun 5. doi: 10.1038/s41556-024-01436-5. Online ahead of print. Nat Cell Biol. 2024. PMID: 38839979
Prominent tauopathy and intracellular β-amyloid accumulation triggered by genetic deletion of cathepsin D: Implications for Alzheimer disease pathogenesis.
Terron HM, Parikh SJ, Abdul-Hay SO, Sahara T, Kang D, Dickson DW, Saftig P, LaFerla FM, Lane S, Leissring MA. Terron HM, et al. Among authors: saftig p. Res Sq [Preprint]. 2023 Oct 23:rs.3.rs-3464352. doi: 10.21203/rs.3.rs-3464352/v1. Res Sq. 2023. PMID: 37961253 Free PMC article. Updated. Preprint.
341 results