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Hyperoside alleviates toxicity of β-amyloid via endoplasmic reticulum-mitochondrial calcium signal transduction cascade in APP/PS1 double transgenic Alzheimer's disease mice.
Song LL, Qu YQ, Tang YP, Chen X, Lo HH, Qu LQ, Yun YX, Wong VKW, Zhang RL, Wang HM, Liu MH, Zhang W, Zhang HX, Chan JTW, Wang CR, Wu JH, Law BYK. Song LL, et al. Redox Biol. 2023 May;61:102637. doi: 10.1016/j.redox.2023.102637. Epub 2023 Feb 14. Redox Biol. 2023. PMID: 36821955 Free PMC article.
Lychee seed polyphenol protects the blood-brain barrier through inhibiting Aβ(25-35)-induced NLRP3 inflammasome activation via the AMPK/mTOR/ULK1-mediated autophagy in bEnd.3 cells and APP/PS1 mice.
Xiong R, Zhou XG, Tang Y, Wu JM, Sun YS, Teng JF, Pan R, Law BY, Zhao Y, Qiu WQ, Wang XL, Liu S, Wang YL, Yu L, Yu CL, Mei QB, Qin DL, Wu AG. Xiong R, et al. Among authors: tang y. Phytother Res. 2021 Feb;35(2):954-973. doi: 10.1002/ptr.6849. Epub 2020 Sep 6. Phytother Res. 2021. PMID: 32893437
Saponins isolated from Radix polygalae extent lifespan by modulating complement C3 and gut microbiota.
Zeng W, Wu AG, Zhou XG, Khan I, Zhang RL, Lo HH, Qu LQ, Song LL, Yun XY, Wang HM, Chen J, Ng JPL, Ren F, Yuan SY, Yu L, Tang Y, Huang GX, Wong VKW, Chung SK, Mok SWF, Qin DL, Sun HL, Liu L, Hsiao WLW, Law BYK. Zeng W, et al. Among authors: tang y. Pharmacol Res. 2021 Aug;170:105697. doi: 10.1016/j.phrs.2021.105697. Epub 2021 May 29. Pharmacol Res. 2021. PMID: 34062240
Targeting autophagy in ethnomedicine against human diseases.
Lai J, Tang Y, Yang F, Chen J, Huang FH, Yang J, Wang L, Qin D, Law BY, Wu AG, Wu JM. Lai J, et al. Among authors: tang y. J Ethnopharmacol. 2022 Jan 10;282:114516. doi: 10.1016/j.jep.2021.114516. Epub 2021 Sep 3. J Ethnopharmacol. 2022. PMID: 34487846
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