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Metformin increases the uptake of glucose into the gut from the circulation in high-fat diet-fed male mice, which is enhanced by a reduction in whole-body Slc2a2 expression.
Morrice N, Vainio S, Mikkola K, van Aalten L, Gallagher JR, Ashford MLJ, McNeilly AD, McCrimmon RJ, Grosfeld A, Serradas P, Koffert J, Pearson ER, Nuutila P, Sutherland C. Morrice N, et al. Among authors: ashford mlj. Mol Metab. 2023 Nov;77:101807. doi: 10.1016/j.molmet.2023.101807. Epub 2023 Sep 16. Mol Metab. 2023. PMID: 37717665 Free PMC article.
Chronic hyperglycaemia increases the vulnerability of the hippocampus to oxidative damage induced during post-hypoglycaemic hyperglycaemia in a mouse model of chemically induced type 1 diabetes.
McNeilly AD, Gallagher JR, Evans ML, de Galan BE, Pedersen-Bjergaard U, Thorens B, Dinkova-Kostova AT, Huang JT, Ashford MLJ, McCrimmon RJ; Hypo-RESOLVE Consortium. McNeilly AD, et al. Among authors: ashford mlj. Diabetologia. 2023 Jul;66(7):1340-1352. doi: 10.1007/s00125-023-05907-6. Epub 2023 Apr 4. Diabetologia. 2023. PMID: 37015997 Free PMC article.
A multi-disciplinary commentary on preclinical research to investigate vascular contributions to dementia.
Sri S, Greenstein A, Granata A, Collcutt A, Jochems ACC, McColl BW, Castro BD, Webber C, Reyes CA, Hall C, Lawrence CB, Hawkes C, Pegasiou-Davies CM, Gibson C, Crawford CL, Smith C, Vivien D, McLean FH, Wiseman F, Brezzo G, Lalli G, Pritchard HAT, Markus HS, Bravo-Ferrer I, Taylor J, Leiper J, Berwick J, Gan J, Gallacher J, Moss J, Goense J, McMullan L, Work L, Evans L, Stringer MS, Ashford M, Abulfadl M, Conlon N, Malhotra P, Bath P, Canter R, Brown R, Ince S, Anderle S, Young S, Quick S, Szymkowiak S, Hill S, Allan S, Wang T, Quinn T, Procter T, Farr TD, Zhao X, Yang Z, Hainsworth AH, Wardlaw JM. Sri S, et al. Among authors: ashford m. Cereb Circ Cogn Behav. 2023 Oct 11;5:100189. doi: 10.1016/j.cccb.2023.100189. eCollection 2023. Cereb Circ Cogn Behav. 2023. PMID: 37941765 Free PMC article. Review.
Corrigendum to "The BACE1 product sAPPβ induces ER stress and inflammation and impairs insulin signaling" [Metab Clin Exp 85 (2018) 59-75].
Botteri G, Salvadó L, Gumà A, Hamilton DL, Meakin PJ, Montagut G, Ashford MLJ, Ceperuelo-Mallafré V, Fernández-Veledo S, Vendrell J, Calderón-Dominguez M, Serra D, Herrero L, Pizarro J, Barroso E, Palomer X, Vázquez-Carrera M. Botteri G, et al. Among authors: ashford mlj. Metabolism. 2019 Jul;96:101-102. doi: 10.1016/j.metabol.2019.04.009. Epub 2019 Apr 18. Metabolism. 2019. PMID: 31005247 No abstract available.
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