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Stressed target cancer cells drive nongenetic reprogramming of CAR T cells and solid tumor microenvironment.
Wang Y, Drum DL, Sun R, Zhang Y, Chen F, Sun F, Dal E, Yu L, Jia J, Arya S, Jia L, Fan S, Isakoff SJ, Kehlmann AM, Dotti G, Liu F, Zheng H, Ferrone CR, Taghian AG, DeLeo AB, Ventin M, Cattaneo G, Li Y, Jounaidi Y, Huang P, Maccalli C, Zhang H, Wang C, Yang J, Boland GM, Sadreyev RI, Wong L, Ferrone S, Wang X. Wang Y, et al. Among authors: zhang h, zhang y. Nat Commun. 2023 Sep 15;14(1):5727. doi: 10.1038/s41467-023-41282-x. Nat Commun. 2023. PMID: 37714830 Free PMC article.
Single-cell analysis of immune and stroma cell remodeling in clear cell renal cell carcinoma primary tumors and bone metastatic lesions.
Mei S, Alchahin AM, Tsea I, Kfoury Y, Hirz T, Jeffries NE, Zhao T, Xu Y, Zhang H, Sarkar H, Wu S, Subtelny AO, Johnsen JI, Zhang Y, Salari K, Wu CL, Randolph MA, Scadden DT, Dahl DM, Shin J, Kharchenko PV, Saylor PJ, Sykes DB, Baryawno N. Mei S, et al. Among authors: zhang h, zhang y. Genome Med. 2024 Jan 29;16(1):1. doi: 10.1186/s13073-023-01272-6. Genome Med. 2024. PMID: 38281962 Free PMC article.
Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress.
Do BT, Hsu PP, Vermeulen SY, Wang Z, Hirz T, Abbott KL, Aziz N, Replogle JM, Bjelosevic S, Paolino J, Nelson SA, Block S, Darnell AM, Ferreira R, Zhang H, Milosevic J, Schmidt DR, Chidley C, Harris IS, Weissman JS, Pikman Y, Stegmaier K, Cheloufi S, Su XA, Sykes DB, Vander Heiden MG. Do BT, et al. Among authors: zhang h. Dev Cell. 2024 May 30:S1534-5807(24)00327-7. doi: 10.1016/j.devcel.2024.05.010. Online ahead of print. Dev Cell. 2024. PMID: 38823395
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