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Heparins are potent inhibitors of ectonucleotide pyrophosphatase/phospho-diesterase-1 (NPP1) - a promising target for the immunotherapy of cancer.
Front Immunol. 2023 Aug 29;14:1173634. doi: 10.3389/fimmu.2023.1173634. eCollection 2023.
Front Immunol. 2023.
PMID: 37711611
Free PMC article.
Sulfated Polysaccharides from Macroalgae Are Potent Dual Inhibitors of Human ATP-Hydrolyzing Ectonucleotidases NPP1 and CD39.
Lopez V, Schäkel L, Schuh HJM, Schmidt MS, Mirza S, Renn C, Pelletier J, Lee SY, Sévigny J, Alban S, Bendas G, Müller CE.
Lopez V, et al. Among authors: schuh hjm.
Mar Drugs. 2021 Jan 22;19(2):51. doi: 10.3390/md19020051.
Mar Drugs. 2021.
PMID: 33499103
Free PMC article.
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