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Heparins are potent inhibitors of ectonucleotide pyrophosphatase/phospho-diesterase-1 (NPP1) - a promising target for the immunotherapy of cancer.
Lopez V, Schuh HJM, Mirza S, Vaaßen VJ, Schmidt MS, Sylvester K, Idris RM, Renn C, Schäkel L, Pelletier J, Sévigny J, Naggi A, Scheffler B, Lee SY, Bendas G, Müller CE. Lopez V, et al. Among authors: pelletier j. Front Immunol. 2023 Aug 29;14:1173634. doi: 10.3389/fimmu.2023.1173634. eCollection 2023. Front Immunol. 2023. PMID: 37711611 Free PMC article.
Design and synthesis of new adamantyl derivatives as promising antiproliferative agents.
Shahin AI, Zaraei SO, AlKubaisi BO, Ullah S, Anbar HS, El-Gamal R, Menon V, Abdel-Maksoud MS, Oh CH, El-Awady R, Gelsleichter NE, Pelletier J, Sévigny J, Iqbal J, Al-Tel TH, El-Gamal MI. Shahin AI, et al. Among authors: pelletier j. Eur J Med Chem. 2023 Jan 15;246:114958. doi: 10.1016/j.ejmech.2022.114958. Epub 2022 Nov 26. Eur J Med Chem. 2023. PMID: 36470105
Synthesis, in vitro, and in silico studies of morpholine-based thiosemicarbazones as ectonucleotide pyrophosphatase/phosphodiesterase-1 and -3 inhibitors.
Tasleem M, Pelletier J, Sévigny J, Hussain Z, Khan A, Al-Harrasi A, El-Kott AF, Taslimi P, Negm S, Shafiq Z, Iqbal J. Tasleem M, et al. Among authors: pelletier j. Int J Biol Macromol. 2024 May;266(Pt 2):131068. doi: 10.1016/j.ijbiomac.2024.131068. Epub 2024 Mar 24. Int J Biol Macromol. 2024. PMID: 38531526
1,994 results