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Heparins are potent inhibitors of ectonucleotide pyrophosphatase/phospho-diesterase-1 (NPP1) - a promising target for the immunotherapy of cancer.
Lopez V, Schuh HJM, Mirza S, Vaaßen VJ, Schmidt MS, Sylvester K, Idris RM, Renn C, Schäkel L, Pelletier J, Sévigny J, Naggi A, Scheffler B, Lee SY, Bendas G, Müller CE. Lopez V, et al. Among authors: idris rm. Front Immunol. 2023 Aug 29;14:1173634. doi: 10.3389/fimmu.2023.1173634. eCollection 2023. Front Immunol. 2023. PMID: 37711611 Free PMC article.
Fluorescent Probes for Ecto-5'-nucleotidase (CD73).
Schmies CC, Rolshoven G, Idris RM, Losenkova K, Renn C, Schäkel L, Al-Hroub H, Wang Y, Garofano F, Schmidt-Wolf IGH, Zimmermann H, Yegutkin GG, Müller CE. Schmies CC, et al. Among authors: idris rm. ACS Med Chem Lett. 2020 Sep 3;11(11):2253-2260. doi: 10.1021/acsmedchemlett.0c00391. eCollection 2020 Nov 12. ACS Med Chem Lett. 2020. PMID: 33214837 Free PMC article.
Structure-Activity Relationship of 3-Methylcytidine-5'-α,β-methylenediphosphates as CD73 Inhibitors.
Scortichini M, Idris RM, Moschütz S, Keim A, Salmaso V, Dobelmann C, Oliva P, Losenkova K, Irjala H, Vaittinen S, Sandholm J, Yegutkin GG, Sträter N, Junker A, Müller CE, Jacobson KA. Scortichini M, et al. Among authors: idris rm. J Med Chem. 2022 Feb 10;65(3):2409-2433. doi: 10.1021/acs.jmedchem.1c01852. Epub 2022 Jan 26. J Med Chem. 2022. PMID: 35080883 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 35554636