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Synthesis of stable analogues of geranylgeranyl diphosphate possessing a (Z,E,E)-geranylgeranyl side chain, docking analysis, and biological assays for prenyl protein transferase inhibition.
Minutolo F, Bertini S, Betti L, Danesi R, Gervasi G, Giannaccini G, Martinelli A, Papini AM, Peroni E, Placanica G, Rapposelli S, Tuccinardi T, Macchia M. Minutolo F, et al. Among authors: macchia m. ChemMedChem. 2006 Feb;1(2):218-24. doi: 10.1002/cmdc.200500010. ChemMedChem. 2006. PMID: 16892354
alpha-Naphthylaminopropan-2-ol Derivatives as BACE1 Inhibitors.
Asso V, Ghilardi E, Bertini S, Digiacomo M, Granchi C, Minutolo F, Rapposelli S, Bortolato A, Moro S, Macchia M. Asso V, et al. Among authors: macchia m. ChemMedChem. 2008 Oct;3(10):1530-4. doi: 10.1002/cmdc.200800162. ChemMedChem. 2008. PMID: 18781572 No abstract available.
Discovery of N-hydroxyindole-based inhibitors of human lactate dehydrogenase isoform A (LDH-A) as starvation agents against cancer cells.
Granchi C, Roy S, Giacomelli C, Macchia M, Tuccinardi T, Martinelli A, Lanza M, Betti L, Giannaccini G, Lucacchini A, Funel N, León LG, Giovannetti E, Peters GJ, Palchaudhuri R, Calvaresi EC, Hergenrother PJ, Minutolo F. Granchi C, et al. Among authors: macchia m. J Med Chem. 2011 Mar 24;54(6):1599-612. doi: 10.1021/jm101007q. Epub 2011 Feb 18. J Med Chem. 2011. PMID: 21332213
212 results