Bailey D - Search Results

1

Predicting the target landscape of kinase inhibitors using 3D convolutional neural networks.

Kanev GK, Zhang Y, Kooistra AJ, Bender A, Leurs R, Bailey D, Würdinger T, de Graaf C, de Esch IJP, Westerman BA. Kanev GK, et al. Among authors: bailey d. PLoS Comput Biol. 2023 Sep 5;19(9):e1011301. doi: 10.1371/journal.pcbi.1011301. eCollection 2023 Sep. PLoS Comput Biol. 2023. PMID: 37669273 Free PMC article.

2

Discovery of novel Trypanosoma brucei phosphodiesterase B1 inhibitors by virtual screening against the unliganded TbrPDEB1 crystal structure.

Jansen C, Wang H, Kooistra AJ, de Graaf C, Orrling KM, Tenor H, Seebeck T, Bailey D, de Esch IJ, Ke H, Leurs R. Jansen C, et al. Among authors: bailey d. J Med Chem. 2013 Mar 14;56(5):2087-96. doi: 10.1021/jm3017877. Epub 2013 Mar 1. J Med Chem. 2013. PMID: 23409953 Free PMC article.

3

GBM Drug Bank-a new resource for glioblastoma drug discovery and informatics research.

Svensson F, Westerman B, Würdinger T, Bailey D. Svensson F, et al. Among authors: bailey d. Neuro Oncol. 2018 Nov 12;20(12):1680-1681. doi: 10.1093/neuonc/noy122. Neuro Oncol. 2018. PMID: 30137543 Free PMC article. No abstract available.

4

Fragment-Based Drug Discovery of Phosphodiesterase Inhibitors.

Svensson F, Bender A, Bailey D. Svensson F, et al. Among authors: bailey d. J Med Chem. 2018 Feb 22;61(4):1415-1424. doi: 10.1021/acs.jmedchem.7b00404. Epub 2017 Aug 11. J Med Chem. 2018. PMID: 28800229

5

Screening of predicted synergistic multi-target therapies in glioblastoma identifies new treatment strategies.

Houweling M, Giczewska A, Abdul K, Nieuwenhuis N, Küçükosmanoglu A, Pastuszak K, Buijsman RC, Wesseling P, Wedekind L, Noske D, Supernat A, Bailey D, Watts C, Wurdinger T, Westerman BA. Houweling M, et al. Among authors: bailey d. Neurooncol Adv. 2023 Jun 13;5(1):vdad073. doi: 10.1093/noajnl/vdad073. eCollection 2023 Jan-Dec. Neurooncol Adv. 2023. PMID: 37455945 Free PMC article.

6

Transforming fragments into candidates: small becomes big in medicinal chemistry.

de Kloe GE, Bailey D, Leurs R, de Esch IJ. de Kloe GE, et al. Among authors: bailey d. Drug Discov Today. 2009 Jul;14(13-14):630-46. doi: 10.1016/j.drudis.2009.03.009. Epub 2009 Mar 31. Drug Discov Today. 2009. PMID: 19443265 Review.

7

Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal Activity.

Blaazer AR, Singh AK, de Heuvel E, Edink E, Orrling KM, Veerman JJN, van den Bergh T, Jansen C, Balasubramaniam E, Mooij WJ, Custers H, Sijm M, Tagoe DNA, Kalejaiye TD, Munday JC, Tenor H, Matheeussen A, Wijtmans M, Siderius M, de Graaf C, Maes L, de Koning HP, Bailey DS, Sterk GJ, de Esch IJP, Brown DG, Leurs R. Blaazer AR, et al. Among authors: bailey ds. J Med Chem. 2018 May 10;61(9):3870-3888. doi: 10.1021/acs.jmedchem.7b01670. Epub 2018 May 1. J Med Chem. 2018. PMID: 29672041 Free PMC article.

8

Fragment-based screening in tandem with phenotypic screening provides novel antiparasitic hits.

Blaazer AR, Orrling KM, Shanmugham A, Jansen C, Maes L, Edink E, Sterk GJ, Siderius M, England P, Bailey D, de Esch IJ, Leurs R. Blaazer AR, et al. Among authors: bailey d. J Biomol Screen. 2015 Jan;20(1):131-40. doi: 10.1177/1087057114549735. Epub 2014 Sep 17. J Biomol Screen. 2015. PMID: 25231971

9

The TICking clock of EGFR therapy resistance in glioblastoma: Target Independence or target Compensation.

Saleem H, Kulsoom Abdul U, Küçükosmanoglu A, Houweling M, Cornelissen FMG, Heiland DH, Hegi ME, Kouwenhoven MCM, Bailey D, Würdinger T, Westerman BA. Saleem H, et al. Among authors: bailey d. Drug Resist Updat. 2019 Mar;43:29-37. doi: 10.1016/j.drup.2019.04.002. Epub 2019 Apr 22. Drug Resist Updat. 2019. PMID: 31054489 Free article.

10

Catechol pyrazolinones as trypanocidals: fragment-based design, synthesis, and pharmacological evaluation of nanomolar inhibitors of trypanosomal phosphodiesterase B1.

Orrling KM, Jansen C, Vu XL, Balmer V, Bregy P, Shanmugham A, England P, Bailey D, Cos P, Maes L, Adams E, van den Bogaart E, Chatelain E, Ioset JR, van de Stolpe A, Zorg S, Veerman J, Seebeck T, Sterk GJ, de Esch IJ, Leurs R. Orrling KM, et al. Among authors: bailey d. J Med Chem. 2012 Oct 25;55(20):8745-56. doi: 10.1021/jm301059b. Epub 2012 Oct 8. J Med Chem. 2012. PMID: 22963052

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

2,535 results

Search Page