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GMP manufacture of Shigella flexneri 2a Artificial Invaplex (InvaplexAR) and evaluation in a Phase 1 Open-label, dose escalating study administered intranasally to healthy, adult volunteers.
Vaccine. 2023 Oct 6;41(42):6261-6271. doi: 10.1016/j.vaccine.2023.08.051. Epub 2023 Sep 2.
Vaccine. 2023.
PMID: 37666695
Free article.
Immunization of Rabbits with a Quadrivalent Shigella Bioconjugate Vaccine Induces Functional Antibodies Reactive with Shigella Isolates from Kenya.
Odundo EA, Weerts HP, Musila L, Ogonda L, Dreyer AM, Schneider J, Carranza P, Kaminski RW.
Odundo EA, et al. Among authors: weerts hp.
mSphere. 2022 Jun 29;7(3):e0102021. doi: 10.1128/msphere.01020-21. Epub 2022 May 25.
mSphere. 2022.
PMID: 35611657
Free PMC article.
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Immune response characterization in a human challenge study with a Shigella flexneri 2a bioconjugate vaccine.
Clarkson KA, Talaat KR, Alaimo C, Martin P, Bourgeois AL, Dreyer A, Porter CK, Chakraborty S, Brubaker J, Elwood D, Frölich R, DeNearing B, Weerts HP, Feijoo B, Halpern J, Sack D, Riddle MS, Fonck VG, Kaminski RW.
Clarkson KA, et al. Among authors: weerts hp.
EBioMedicine. 2021 Apr;66:103308. doi: 10.1016/j.ebiom.2021.103308. Epub 2021 Apr 1.
EBioMedicine. 2021.
PMID: 33813141
Free PMC article.
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Immune Response Characterization after Controlled Infection with Lyophilized Shigella sonnei 53G.
Clarkson KA, Frenck RW Jr, Dickey M, Suvarnapunya AE, Chandrasekaran L, Weerts HP, Heaney CD, McNeal M, Detizio K, Parker S, Hoeper A, Bourgeois AL, Porter CK, Venkatesan MM, Kaminski RW.
Clarkson KA, et al. Among authors: weerts hp.
mSphere. 2020 Sep 23;5(5):e00988-19. doi: 10.1128/mSphere.00988-19.
mSphere. 2020.
PMID: 32968012
Free PMC article.
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A High-throughput Shigella-specific Bactericidal Assay.
Weerts HP, Yu J, Kaminski RW, Nahm MH.
Weerts HP, et al.
J Vis Exp. 2019 Feb 27;(144). doi: 10.3791/59164.
J Vis Exp. 2019.
PMID: 30882773
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Development, Interlaboratory Evaluations, and Application of a Simple, High-Throughput Shigella Serum Bactericidal Assay.
Nahm MH, Yu J, Weerts HP, Wenzel H, Tamilselvi CS, Chandrasekaran L, Pasetti MF, Mani S, Kaminski RW.
Nahm MH, et al. Among authors: weerts hp.
mSphere. 2018 Jun 13;3(3):e00146-18. doi: 10.1128/mSphere.00146-18. Print 2018 Jun 27.
mSphere. 2018.
PMID: 29898979
Free PMC article.
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