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Opsonization-independent antigen-specific recognition by myeloid phagocytes expressing monoclonal antibodies.
Sci Adv. 2023 Sep;9(35):eadg1812. doi: 10.1126/sciadv.adg1812. Epub 2023 Sep 1.
Sci Adv. 2023.
PMID: 37656789
Free article.
Combinatorial BCL2 Family Expression in Acute Myeloid Leukemia Stem Cells Predicts Clinical Response to Azacitidine/Venetoclax.
Waclawiczek A, Leppä AM, Renders S, Stumpf K, Reyneri C, Betz B, Janssen M, Shahswar R, Donato E, Karpova D, Thiel V, Unglaub JM, Grabowski S, Gryzik S, Vierbaum L, Schlenk RF, Röllig C, Hundemer M, Pabst C, Heuser M, Raffel S, Müller-Tidow C, Sauer T, Trumpp A.
Waclawiczek A, et al. Among authors: leppa am.
Cancer Discov. 2023 Jun 2;13(6):1408-1427. doi: 10.1158/2159-8290.CD-22-0939.
Cancer Discov. 2023.
PMID: 36892565
Free PMC article.
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Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia.
Kuusanmäki H, Dufva O, Vähä-Koskela M, Leppä AM, Huuhtanen J, Vänttinen I, Nygren P, Klievink J, Bouhlal J, Pölönen P, Zhang Q, Adnan-Awad S, Mancebo-Pérez C, Saad J, Miettinen J, Javarappa KK, Aakko S, Ruokoranta T, Eldfors S, Heinäniemi M, Theilgaard-Mönch K, Wartiovaara-Kautto U, Keränen M, Porkka K, Konopleva M, Wennerberg K, Kontro M, Heckman CA, Mustjoki S.
Kuusanmäki H, et al. Among authors: leppa am.
Blood. 2023 Mar 30;141(13):1610-1625. doi: 10.1182/blood.2021011094.
Blood. 2023.
PMID: 36508699
Free PMC article.
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An arms-race against resistance: leukemic stem cells and lineage plasticity.
Waclawiczek A, Leppä AM, Renders S, Trumpp A.
Waclawiczek A, et al. Among authors: leppa am.
Mol Oncol. 2024 Mar;18(3):475-478. doi: 10.1002/1878-0261.13606. Epub 2024 Feb 20.
Mol Oncol. 2024.
PMID: 38375990
Free PMC article.
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Multi-parametric single cell evaluation defines distinct drug responses in healthy hematologic cells that are retained in corresponding malignant cell types.
Majumder MM, Leppä AM, Hellesøy M, Dowling P, Malyutina A, Kopperud R, Bazou D, Andersson E, Parsons A, Tang J, Kallioniemi O, Mustjoki S, O'Gorman P, Wennerberg K, Porkka K, Gjertsen BT, Heckman CA.
Majumder MM, et al. Among authors: leppa am.
Haematologica. 2020 Jun;105(6):1527-1538. doi: 10.3324/haematol.2019.217414. Epub 2019 Aug 22.
Haematologica. 2020.
PMID: 31439679
Free PMC article.
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Phenotype-based drug screening reveals association between venetoclax response and differentiation stage in acute myeloid leukemia.
Kuusanmäki H, Leppä AM, Pölönen P, Kontro M, Dufva O, Deb D, Yadav B, Brück O, Kumar A, Everaus H, Gjertsen BT, Heinäniemi M, Porkka K, Mustjoki S, Heckman CA.
Kuusanmäki H, et al. Among authors: leppa am.
Haematologica. 2020 Mar;105(3):708-720. doi: 10.3324/haematol.2018.214882. Epub 2019 Jul 11.
Haematologica. 2020.
PMID: 31296572
Free PMC article.
No abstract available.
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