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Intramacrophage lipid accumulation compromises T cell responses and is associated with impaired drug therapy against visceral leishmaniasis.
Araújo M, Moreira D, Mesquita I, Ferreira C, Mendes-Frias A, Barros-Carvalho S, Dinis-Oliveira RJ, Duarte-Oliveira C, Cunha C, Carvalho A, Saha B, Cordeiro-da-Silva A, Estaquier J, Silvestre R. Araújo M, et al. Among authors: mesquita i. Immunology. 2023 Dec;170(4):510-526. doi: 10.1111/imm.13686. Epub 2023 Aug 27. Immunology. 2023. PMID: 37635289
The Absence of HIF-1α Increases Susceptibility to Leishmania donovani Infection via Activation of BNIP3/mTOR/SREBP-1c Axis.
Mesquita I, Ferreira C, Moreira D, Kluck GEG, Barbosa AM, Torrado E, Dinis-Oliveira RJ, Gonçalves LG, Beauparlant CJ, Droit A, Berod L, Sparwasser T, Bodhale N, Saha B, Rodrigues F, Cunha C, Carvalho A, Castro AG, Estaquier J, Silvestre R. Mesquita I, et al. Cell Rep. 2020 Mar 24;30(12):4052-4064.e7. doi: 10.1016/j.celrep.2020.02.098. Cell Rep. 2020. PMID: 32209468 Free article.
Leishmania donovani Induces Multiple Dynamic Responses in the Metabolome Associated with Amastigote Differentiation and Maturation Inside the Human Macrophage.
Fernández-García M, Mesquita I, Ferreira C, Araújo M, Saha B, Rey-Stolle MF, García A, Silvestre R, Barbas C. Fernández-García M, et al. Among authors: mesquita i. J Proteome Res. 2023 Jul 7;22(7):2256-2270. doi: 10.1021/acs.jproteome.2c00845. Epub 2023 Jun 20. J Proteome Res. 2023. PMID: 37339249 Review.
AMPK in Pathogens.
Mesquita I, Moreira D, Sampaio-Marques B, Laforge M, Cordeiro-da-Silva A, Ludovico P, Estaquier J, Silvestre R. Mesquita I, et al. Exp Suppl. 2016;107:287-323. doi: 10.1007/978-3-319-43589-3_12. Exp Suppl. 2016. PMID: 27812985 Review.
IL-10 overexpression predisposes to invasive aspergillosis by suppressing antifungal immunity.
Cunha C, Gonçalves SM, Duarte-Oliveira C, Leite L, Lagrou K, Marques A, Lupiañez CB, Mesquita I, Gaifem J, Barbosa AM, Pinho Vaz C, Branca R, Campilho F, Freitas F, Ligeiro D, Lass-Flörl C, Löffler J, Jurado M, Saraiva M, Kurzai O, Rodrigues F, Castro AG, Silvestre R, Sainz J, Maertens JA, Torrado E, Jacobsen ID, Lacerda JF, Campos A Jr, Carvalho A. Cunha C, et al. Among authors: mesquita i. J Allergy Clin Immunol. 2017 Sep;140(3):867-870.e9. doi: 10.1016/j.jaci.2017.02.034. Epub 2017 Apr 4. J Allergy Clin Immunol. 2017. PMID: 28389392 Free article. No abstract available.
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