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4'-Demethylnobiletin, a bioactive metabolite of nobiletin enhancing PKA/ERK/CREB signaling, rescues learning impairment associated with NMDA receptor antagonism via stimulation of the ERK cascade.
Al Rahim M, Nakajima A, Saigusa D, Tetsu N, Maruyama Y, Shibuya M, Yamakoshi H, Tomioka Y, Iwabuchi Y, Ohizumi Y, Yamakuni T. Al Rahim M, et al. Among authors: saigusa d. Biochemistry. 2009 Aug 18;48(32):7713-21. doi: 10.1021/bi901088w. Biochemistry. 2009. PMID: 19601643
Simultaneous quantitation of sphingoid bases and their phosphates in biological samples by liquid chromatography/electrospray ionization tandem mass spectrometry.
Saigusa D, Shiba K, Inoue A, Hama K, Okutani M, Iida N, Saito M, Suzuki K, Kaneko T, Suzuki N, Yamaguchi H, Mano N, Goto J, Hishinuma T, Aoki J, Tomioka Y. Saigusa D, et al. Anal Bioanal Chem. 2012 Jun;403(7):1897-905. doi: 10.1007/s00216-012-6004-9. Epub 2012 Apr 27. Anal Bioanal Chem. 2012. PMID: 22538778
Metabolic alterations by indoxyl sulfate in skeletal muscle induce uremic sarcopenia in chronic kidney disease.
Sato E, Mori T, Mishima E, Suzuki A, Sugawara S, Kurasawa N, Saigusa D, Miura D, Morikawa-Ichinose T, Saito R, Oba-Yabana I, Oe Y, Kisu K, Naganuma E, Koizumi K, Mokudai T, Niwano Y, Kudo T, Suzuki C, Takahashi N, Sato H, Abe T, Niwa T, Ito S. Sato E, et al. Among authors: saigusa d. Sci Rep. 2016 Nov 10;6:36618. doi: 10.1038/srep36618. Sci Rep. 2016. PMID: 27830716 Free PMC article.
127 results