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Platelet factors attenuate inflammation and rescue cognition in ageing.
Schroer AB, Ventura PB, Sucharov J, Misra R, Chui MKK, Bieri G, Horowitz AM, Smith LK, Encabo K, Tenggara I, Couthouis J, Gross JD, Chan JM, Luke A, Villeda SA. Schroer AB, et al. Among authors: villeda sa. Nature. 2023 Aug;620(7976):1071-1079. doi: 10.1038/s41586-023-06436-3. Epub 2023 Aug 16. Nature. 2023. PMID: 37587343 Free PMC article.
The ageing systemic milieu negatively regulates neurogenesis and cognitive function.
Villeda SA, Luo J, Mosher KI, Zou B, Britschgi M, Bieri G, Stan TM, Fainberg N, Ding Z, Eggel A, Lucin KM, Czirr E, Park JS, Couillard-Després S, Aigner L, Li G, Peskind ER, Kaye JA, Quinn JF, Galasko DR, Xie XS, Rando TA, Wyss-Coray T. Villeda SA, et al. Nature. 2011 Aug 31;477(7362):90-4. doi: 10.1038/nature10357. Nature. 2011. PMID: 21886162 Free PMC article.
Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner.
Deczkowska A, Matcovitch-Natan O, Tsitsou-Kampeli A, Ben-Hamo S, Dvir-Szternfeld R, Spinrad A, Singer O, David E, Winter DR, Smith LK, Kertser A, Baruch K, Rosenzweig N, Terem A, Prinz M, Villeda S, Citri A, Amit I, Schwartz M. Deczkowska A, et al. Nat Commun. 2017 Sep 28;8(1):717. doi: 10.1038/s41467-017-00769-0. Nat Commun. 2017. PMID: 28959042 Free PMC article.
Proteolytic cleavage of Beclin 1 exacerbates neurodegeneration.
Bieri G, Lucin KM, O'Brien CE, Zhang H, Villeda SA, Wyss-Coray T. Bieri G, et al. Among authors: villeda sa. Mol Neurodegener. 2018 Dec 29;13(1):68. doi: 10.1186/s13024-018-0302-4. Mol Neurodegener. 2018. PMID: 30594228 Free PMC article.
58 results