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Evolutionary Aspects of TRPMLs and TPCs.
Jaślan D, Böck J, Krogsaeter E, Grimm C. Jaślan D, et al. Among authors: grimm c. Int J Mol Sci. 2020 Jun 11;21(11):4181. doi: 10.3390/ijms21114181. Int J Mol Sci. 2020. PMID: 32545371 Free PMC article. Review.
TPC1 deficiency or blockade augments systemic anaphylaxis and mast cell activity.
Arlt E, Fraticelli M, Tsvilovskyy V, Nadolni W, Breit A, O'Neill TJ, Resenberger S, Wennemuth G, Wahl-Schott C, Biel M, Grimm C, Freichel M, Gudermann T, Klugbauer N, Boekhoff I, Zierler S. Arlt E, et al. Among authors: grimm c. Proc Natl Acad Sci U S A. 2020 Jul 28;117(30):18068-18078. doi: 10.1073/pnas.1920122117. Epub 2020 Jul 13. Proc Natl Acad Sci U S A. 2020. PMID: 32661165 Free PMC article.
Segregated cation flux by TPC2 biases Ca2+ signaling through lysosomes.
Yuan Y, Jaślan D, Rahman T, Bolsover SR, Arige V, Wagner LE 2nd, Abrahamian C, Tang R, Keller M, Hartmann J, Rosato AS, Weiden EM, Bracher F, Yule DI, Grimm C, Patel S. Yuan Y, et al. Among authors: grimm c. Nat Commun. 2022 Aug 2;13(1):4481. doi: 10.1038/s41467-022-31959-0. Nat Commun. 2022. PMID: 35918320 Free PMC article.
TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann-Pick type C1, and Batten disease.
Scotto Rosato A, Krogsaeter EK, Jaślan D, Abrahamian C, Montefusco S, Soldati C, Spix B, Pizzo MT, Grieco G, Böck J, Wyatt A, Wünkhaus D, Passon M, Stieglitz M, Keller M, Hermey G, Markmann S, Gruber-Schoffnegger D, Cotman S, Johannes L, Crusius D, Boehm U, Wahl-Schott C, Biel M, Bracher F, De Leonibus E, Polishchuk E, Medina DL, Paquet D, Grimm C. Scotto Rosato A, et al. Among authors: grimm c. EMBO Mol Med. 2022 Sep 7;14(9):e15377. doi: 10.15252/emmm.202115377. Epub 2022 Aug 5. EMBO Mol Med. 2022. PMID: 35929194 Free PMC article.
TRPML3.
Grimm C, Barthmes M, Wahl-Schott C. Grimm C, et al. Handb Exp Pharmacol. 2014;222:659-74. doi: 10.1007/978-3-642-54215-2_26. Handb Exp Pharmacol. 2014. PMID: 24756725 Review.
Endolysosomal TPCs regulate social behavior by controlling oxytocin secretion.
Martucci LL, Launay JM, Kawakami N, Sicard C, Desvignes N, Dakouane-Giudicelli M, Spix B, Têtu M, Gilmaire FO, Paulcan S, Callebert J, Vaillend C, Bracher F, Grimm C, Fossier P, de la Porte S, Sakamoto H, Morris J, Galione A, Granon S, Cancela JM. Martucci LL, et al. Among authors: grimm c. Proc Natl Acad Sci U S A. 2023 Feb 14;120(7):e2213682120. doi: 10.1073/pnas.2213682120. Epub 2023 Feb 6. Proc Natl Acad Sci U S A. 2023. PMID: 36745816 Free PMC article.
Endolysosomal Cation Channels and Lung Disease.
Spix B, Jeridi A, Ansari M, Yildirim AÖ, Schiller HB, Grimm C. Spix B, et al. Among authors: grimm c. Cells. 2022 Jan 17;11(2):304. doi: 10.3390/cells11020304. Cells. 2022. PMID: 35053420 Free PMC article. Review.
740 results