Handzlik J - Search Results

1

Synthesis, computational and experimental pharmacological studies for (thio)ether-triazine 5-HT₆R ligands with noticeable action on AChE/BChE and chalcogen-dependent intrinsic activity in search for new class of drugs against Alzheimer's disease.

Czarnota-Łydka K, Sudoł-Tałaj S, Kucwaj-Brysz K, Kurczab R, Satała G, de Candia M, Samarelli F, Altomare CD, Carocci A, Barbarossa A, Żesławska E, Głuch-Lutwin M, Mordyl B, Kubacka M, Wilczyńska-Zawal N, Jastrzębska-Więsek M, Partyka A, Khan N, Więcek M, Nitek W, Honkisz-Orzechowska E, Latacz G, Wesołowska A, Carrieri A, Handzlik J. Czarnota-Łydka K, et al. Among authors: handzlik j. Eur J Med Chem. 2023 Nov 5;259:115695. doi: 10.1016/j.ejmech.2023.115695. Epub 2023 Jul 30. Eur J Med Chem. 2023. PMID: 37567058 Free article.

2

In vitro cytotoxic activity evaluation of phenytoin derivatives against human leukemia cells.

Śladowska K, Handzlik J, Kieć-Kononowicz K, Mazur L. Śladowska K, et al. Among authors: handzlik j. Indian J Exp Biol. 2016 Sep;54(9):553-9. Indian J Exp Biol. 2016. PMID: 28699720

3

Biological activity of twenty-three hydantoin derivatives on intrinsic efflux pump system of Salmonella enterica serovar Enteritidis NCTC 13349.

Machado L, Spengler G, Evaristo M, Handzlik J, Molnár J, Viveiros M, Kiec-Kononowicz K, Amaral L. Machado L, et al. Among authors: handzlik j. In Vivo. 2011 Sep-Oct;25(5):769-72. In Vivo. 2011. PMID: 21753132

4

Strategies for bypassing the membrane barrier in multidrug resistant Gram-negative bacteria.

Bolla JM, Alibert-Franco S, Handzlik J, Chevalier J, Mahamoud A, Boyer G, Kieć-Kononowicz K, Pagès JM. Bolla JM, et al. Among authors: handzlik j. FEBS Lett. 2011 Jun 6;585(11):1682-90. doi: 10.1016/j.febslet.2011.04.054. Epub 2011 May 3. FEBS Lett. 2011. PMID: 21549704 Free article. Review.

5

Modulation of multidrug efflux pump activity by new hydantoin derivatives on colon adenocarcinoma cells without inducing apoptosis.

Spengler G, Handzlik J, Ocsovszki I, Viveiros M, Kiec-Kononowicz K, Molnar J, Amaral L. Spengler G, et al. Among authors: handzlik j. Anticancer Res. 2011 Oct;31(10):3285-8. Anticancer Res. 2011. PMID: 21965738

6

Biological activity of hydantoin derivatives on P-glycoprotein (ABCB1) of mouse lymphoma cells.

Spengler G, Evaristo M, Handzlik J, Serly J, Molnár J, Viveiros M, Kiéc-Kononowicz K, Amaral L. Spengler G, et al. Among authors: handzlik j. Anticancer Res. 2010 Dec;30(12):4867-71. Anticancer Res. 2010. PMID: 21187464

7

Inhibitors of bacterial efflux pumps that also inhibit efflux pumps of cancer cells.

Amaral L, Spengler G, Martins A, Armada A, Handzlik J, Kiec-Kononowicz K, Molnar J. Amaral L, et al. Among authors: handzlik j. Anticancer Res. 2012 Jul;32(7):2947-57. Anticancer Res. 2012. PMID: 22753759 Review.

8

Activity of fourteen new hydantoin compounds on the human ABCB1 efflux pump.

Martins A, Dymek A, Handzlik J, Spengler G, Armada A, Molnar J, Kiéc-Kononowicz K, Amaral L. Martins A, et al. Among authors: handzlik j. In Vivo. 2012 Mar-Apr;26(2):293-7. In Vivo. 2012. PMID: 22351672

9

Novel Piperazine Arylideneimidazolones Inhibit the AcrAB-TolC Pump in Escherichia coli and Simultaneously Act as Fluorescent Membrane Probes in a Combined Real-Time Influx and Efflux Assay.

Bohnert JA, Schuster S, Kern WV, Karcz T, Olejarz A, Kaczor A, Handzlik J, Kieć-Kononowicz K. Bohnert JA, et al. Among authors: handzlik j. Antimicrob Agents Chemother. 2016 Mar 25;60(4):1974-83. doi: 10.1128/AAC.01995-15. Print 2016 Apr. Antimicrob Agents Chemother. 2016. PMID: 26824939 Free PMC article.

10

Synthesis and evaluation of in vivo activity of diphenylhydantoin basic derivatives.

Dylag T, Zygmunt M, Maciag D, Handzlik J, Bednarski M, Filipek B, Kieć-Kononowicz K. Dylag T, et al. Among authors: handzlik j. Eur J Med Chem. 2004 Dec;39(12):1013-27. doi: 10.1016/j.ejmech.2004.05.008. Eur J Med Chem. 2004. PMID: 15571863

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