Offman E - Search Results

1

The Novel GlycoPEGylated FGF21 Analog Pegozafermin Activates Human FGF Receptors and Improves Metabolic and Liver Outcomes in Diabetic Monkeys and Healthy Human Volunteers.

Rosenstock M, Tseng L, Pierce A, Offman E, Chen CY, Charlton RW, Margalit M, Mansbach H. Rosenstock M, et al. Among authors: offman e. J Pharmacol Exp Ther. 2023 Nov;387(2):204-213. doi: 10.1124/jpet.123.001618. Epub 2023 Aug 10. J Pharmacol Exp Ther. 2023. PMID: 37562970

2

Leveraging in vitro and pharmacokinetic models to support bench to bedside investigation of XTMAB-16 as a novel pulmonary sarcoidosis treatment.

Offman E, Singh N, Julian MW, Locke LW, Bicer S, Mitchell J, Matthews T, Anderson K, Crouser ED. Offman E, et al. Front Pharmacol. 2023 Mar 20;14:1066454. doi: 10.3389/fphar.2023.1066454. eCollection 2023. Front Pharmacol. 2023. PMID: 37021060 Free PMC article.

3

Physiologically-based pharmacokinetic modelling to predict intragastric rifabutin concentrations in the treatment of Helicobacter pylori infection.

Howden CW, Shah S, Pendse SN, Offman E, Almenoff JS, Sheldon KL. Howden CW, et al. Among authors: offman e. Aliment Pharmacol Ther. 2023 Jul;58(2):159-167. doi: 10.1111/apt.17526. Epub 2023 Apr 20. Aliment Pharmacol Ther. 2023. PMID: 37081832

4

Brigatinib Dose Rationale in Anaplastic Lymphoma Kinase-Positive Non-Small Cell Lung Cancer: Exposure-Response Analyses of Pivotal ALTA Study.

Gupta N, Wang X, Offman E, Rich B, Kerstein D, Hanley M, Diderichsen PM, Zhang P, Venkatakrishnan K. Gupta N, et al. Among authors: offman e. CPT Pharmacometrics Syst Pharmacol. 2020 Dec;9(12):718-730. doi: 10.1002/psp4.12569. CPT Pharmacometrics Syst Pharmacol. 2020. PMID: 33185028 Free PMC article. Clinical Trial.

5

Population Pharmacokinetics of Brigatinib in Healthy Volunteers and Patients With Cancer.

Gupta N, Wang X, Offman E, Prohn M, Narasimhan N, Kerstein D, Hanley MJ, Venkatakrishnan K. Gupta N, et al. Among authors: offman e. Clin Pharmacokinet. 2021 Feb;60(2):235-247. doi: 10.1007/s40262-020-00929-4. Clin Pharmacokinet. 2021. PMID: 32816246 Free PMC article.

6

A Randomized Comparison of the Pharmacokinetics and Bioavailability of Fluticasone Propionate Delivered via Xhance Exhalation Delivery System Versus Flonase Nasal Spray and Flovent HFA Inhalational Aerosol.

Messina JC, Offman E, Carothers JL, Mahmoud RA. Messina JC, et al. Among authors: offman e. Clin Ther. 2019 Nov;41(11):2343-2356. doi: 10.1016/j.clinthera.2019.09.013. Epub 2019 Nov 12. Clin Ther. 2019. PMID: 31732149 Free article. Clinical Trial.

7

Evaluation of the Potential for Drug Interactions With Patiromer in Healthy Volunteers.

Lesko LJ, Offman E, Brew CT, Garza D, Benton W, Mayo MR, Romero A, Du Mond C, Weir MR. Lesko LJ, et al. Among authors: offman e. J Cardiovasc Pharmacol Ther. 2017 Sep;22(5):434-446. doi: 10.1177/1074248417691135. Epub 2017 Feb 13. J Cardiovasc Pharmacol Ther. 2017. PMID: 28585859 Free PMC article. Clinical Trial.

8

Assessment of pharmacokinetic interaction between omega-3 carboxylic acids and the statins rosuvastatin and simvastatin: Results of 2 phase I studies in healthy volunteers.

Offman E, Davidson M, Nilsson C. Offman E, et al. J Clin Lipidol. 2017 May-Jun;11(3):739-748. doi: 10.1016/j.jacl.2017.03.017. Epub 2017 Apr 5. J Clin Lipidol. 2017. PMID: 28506390 Clinical Trial.

9

No Effect of Omega-3 Carboxylic Acids on Pharmacokinetics/Pharmacodynamics of Warfarin or on Platelet Function When Co-administered with Acetylsalicylic Acid: Results of Two Phase I Studies in Healthy Volunteers.

Offman E, Davidson M, Nilsson C. Offman E, et al. Am J Cardiovasc Drugs. 2017 Jun;17(3):251-260. doi: 10.1007/s40256-017-0217-4. Am J Cardiovasc Drugs. 2017. PMID: 28197979 Clinical Trial.

10

Systemic Bioavailability and Dose Proportionality of Omega-3 Administered in Free Fatty Acid Form Compared With Ethyl Ester Form: Results of a Phase 1 Study in Healthy Volunteers.

Offman E, Davidson M, Abu-Rashid M, Chai P, Nilsson C. Offman E, et al. Eur J Drug Metab Pharmacokinet. 2017 Oct;42(5):815-825. doi: 10.1007/s13318-016-0398-2. Eur J Drug Metab Pharmacokinet. 2017. PMID: 28116646 Clinical Trial.

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